Epstein-Barr virus nuclear antigen 1 (EBNA1) increases the expression levels of MDM2 and MDM4 genes in HeLa cells: a review on MDM2 and MDM4 roles in cancer

Epstein-Barr virus nuclear antigen 1 (EBNA1) increases the expression levels of MDM2 and MDM4 genes in HeLa cells: a review on MDM2 and MDM4 roles in cancer

Abstract Objective Epstein-Barr virus nuclear antigen 1 (EBNA1) is a key viral protein expressed in all latency phases and EBV-associated tumors. It can modulate the expression of various host and viral genes. This study aimed to investigate the impact of EBNA1 on the expression levels of two cellul...

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Bibliographic Details
Main Authors: Seyed Mohammad Ali Hashemi, Amir Hossein Alipour, Sima Emamifar, Ali Farhadi, Jamal Sarvari
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Research Notes
Online Access:https://doi.org/10.1186/s13104-025-07275-3
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