Unveiling new features of the human pathogen Cryptococcus neoformans through the reconstruction and exploitation of a dedicated genome-scale metabolic model

Cryptococcus neoformans is notorious for causing severe pulmonary and central nervous system infections, particularly in immunocompromised patients. High mortality rates, associated with its tropism and adaptation to the brain microenvironment and its drug resistance profile, make this pathogen a pu...

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Bibliographic Details
Main Authors: Romeu Viana, Diogo Couceiro, William Newton, Luís Coutinho, Oscar Dias, Carolina Coelho, Miguel Cacho Teixeira
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Computational and Structural Biotechnology Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S2001037025001989
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