Optimal control of a diffusive epidemiological model involving the Caputo–Fabrizio fractional time-derivative

In this work we study a fractional SEIR biological model of a reaction–diffusion, using the non-singular kernel Caputo–Fabrizio fractional derivative in the Caputo sense and employing the Laplacian operator. In our PDE model, the government seeks immunity through the vaccination program, which is co...

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Bibliographic Details
Main Authors: Achraf Zinihi, Moulay Rchid Sidi Ammi, Matthias Ehrhardt
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Partial Differential Equations in Applied Mathematics
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666818125001159
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Summary:In this work we study a fractional SEIR biological model of a reaction–diffusion, using the non-singular kernel Caputo–Fabrizio fractional derivative in the Caputo sense and employing the Laplacian operator. In our PDE model, the government seeks immunity through the vaccination program, which is considered a control variable. Our study aims to identify the ideal control pair that reduces the number of infected/infectious people and the associated vaccine and treatment costs over a limited time and space. Moreover, by using the forward–backward algorithm, the approximate results are explained by dynamic graphs to monitor the effectiveness of vaccination.
ISSN:2666-8181