Dual Roles of Neutrophil Extracellular Traps in Lung Cancer: Mechanism Exploration and Therapeutic Prospects
Lung cancer is one of the most common and lethal malignancies in China. In the context of the tumor microenvironment, neutrophil extracellular traps (NETs) released by neutrophils exert a profound impact on the occurrence and progression of lung cancer. Although the exact mechanisms by which NETs pr...
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| Format: | Article |
| Language: | zho |
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Chinese Anti-Cancer Association; Chinese Antituberculosis Association
2025-01-01
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| Series: | Chinese Journal of Lung Cancer |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.3779/j.issn.1009-3419.2025.101.01 |
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| _version_ | 1850079713475690496 |
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| author | Chengdao LI Dongge PENG Wei SUN |
| author_facet | Chengdao LI Dongge PENG Wei SUN |
| author_sort | Chengdao LI |
| collection | DOAJ |
| description | Lung cancer is one of the most common and lethal malignancies in China. In the context of the tumor microenvironment, neutrophil extracellular traps (NETs) released by neutrophils exert a profound impact on the occurrence and progression of lung cancer. Although the exact mechanisms by which NETs promote tumor growth have not been fully elucidated, existing research has revealed their multiple roles in tumor growth, invasion, metastasis, and cancer-related thrombosis. This article will review the molecular biology mechanisms and research progress of NETs in lung cancer based on recent studies. |
| format | Article |
| id | doaj-art-5a9779885ee646b2831ecee27b1e5ad2 |
| institution | DOAJ |
| issn | 1009-3419 1999-6187 |
| language | zho |
| publishDate | 2025-01-01 |
| publisher | Chinese Anti-Cancer Association; Chinese Antituberculosis Association |
| record_format | Article |
| series | Chinese Journal of Lung Cancer |
| spelling | doaj-art-5a9779885ee646b2831ecee27b1e5ad22025-08-20T02:45:07ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872025-01-01281636810.3779/j.issn.1009-3419.2025.101.01Dual Roles of Neutrophil Extracellular Traps in Lung Cancer:
Mechanism Exploration and Therapeutic ProspectsChengdao LI0Dongge PENG1Wei SUN2Department of Thoracic Surgery II, Second Affiliated Hospital of Hainan Medical University, Haikou 570311, ChinaDepartment of Thoracic Surgery II, Second Affiliated Hospital of Hainan Medical University, Haikou 570311, ChinaDepartment of Thoracic Surgery II, Second Affiliated Hospital of Hainan Medical University, Haikou 570311, ChinaLung cancer is one of the most common and lethal malignancies in China. In the context of the tumor microenvironment, neutrophil extracellular traps (NETs) released by neutrophils exert a profound impact on the occurrence and progression of lung cancer. Although the exact mechanisms by which NETs promote tumor growth have not been fully elucidated, existing research has revealed their multiple roles in tumor growth, invasion, metastasis, and cancer-related thrombosis. This article will review the molecular biology mechanisms and research progress of NETs in lung cancer based on recent studies.http://dx.doi.org/10.3779/j.issn.1009-3419.2025.101.01neutrophil extracellular trapsneutrophillung neoplasms |
| spellingShingle | Chengdao LI Dongge PENG Wei SUN Dual Roles of Neutrophil Extracellular Traps in Lung Cancer: Mechanism Exploration and Therapeutic Prospects Chinese Journal of Lung Cancer neutrophil extracellular traps neutrophil lung neoplasms |
| title | Dual Roles of Neutrophil Extracellular Traps in Lung Cancer:
Mechanism Exploration and Therapeutic Prospects |
| title_full | Dual Roles of Neutrophil Extracellular Traps in Lung Cancer:
Mechanism Exploration and Therapeutic Prospects |
| title_fullStr | Dual Roles of Neutrophil Extracellular Traps in Lung Cancer:
Mechanism Exploration and Therapeutic Prospects |
| title_full_unstemmed | Dual Roles of Neutrophil Extracellular Traps in Lung Cancer:
Mechanism Exploration and Therapeutic Prospects |
| title_short | Dual Roles of Neutrophil Extracellular Traps in Lung Cancer:
Mechanism Exploration and Therapeutic Prospects |
| title_sort | dual roles of neutrophil extracellular traps in lung cancer
mechanism exploration and therapeutic prospects |
| topic | neutrophil extracellular traps neutrophil lung neoplasms |
| url | http://dx.doi.org/10.3779/j.issn.1009-3419.2025.101.01 |
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