Urachal Carcinoma with Peritoneal Dissemination Treated with Chemotherapy and Surgical Resection Leading to Prolonged Survival with No Recurrence
A 56-year-old man was admitted to our hospital for urachal carcinoma with peritoneal dissemination. He received first-line chemotherapy with gemcitabine and cisplatin. After the fifth cycle, a computed tomography (CT) scan revealed abdominal fluid, and his serum tumor marker levels were increased. T...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Urology |
| Online Access: | http://dx.doi.org/10.1155/2018/9836154 |
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| _version_ | 1832564821456846848 |
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| author | Masato Yasui Ryosuke Jikuya Tomoyuki Tatenuma Kentaro Muraoka Susumu Umemoto Masaki Kawai Tsutomu Kouno Takeshi Kishida |
| author_facet | Masato Yasui Ryosuke Jikuya Tomoyuki Tatenuma Kentaro Muraoka Susumu Umemoto Masaki Kawai Tsutomu Kouno Takeshi Kishida |
| author_sort | Masato Yasui |
| collection | DOAJ |
| description | A 56-year-old man was admitted to our hospital for urachal carcinoma with peritoneal dissemination. He received first-line chemotherapy with gemcitabine and cisplatin. After the fifth cycle, a computed tomography (CT) scan revealed abdominal fluid, and his serum tumor marker levels were increased. The patient was started on second-line therapy with FOLFIRI. After 11 cycles, his tumor decreased in size and no new metastatic lesions were detected. The patient underwent complete tumor resection with partial cystectomy and pelvic lymph node dissection. The tumor was removed, along with adhering surrounding organs, including the omentum, peritoneum, abdominal rectus muscle, and vermiform appendix. Although pathological examination confirmed peritoneal dissemination, his tumor markers normalized soon after surgery. The patient has survived 62 months after surgery without any adjuvant therapy and with no evidence of recurrence. To our knowledge, this is the longest duration of survival without recurrence of a patient with urachal carcinoma with peritoneal dissemination who received multimodal therapy. |
| format | Article |
| id | doaj-art-5a8edcdc92a043b784a397dd5a2884f4 |
| institution | Kabale University |
| issn | 2090-696X 2090-6978 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Urology |
| spelling | doaj-art-5a8edcdc92a043b784a397dd5a2884f42025-02-03T01:10:11ZengWileyCase Reports in Urology2090-696X2090-69782018-01-01201810.1155/2018/98361549836154Urachal Carcinoma with Peritoneal Dissemination Treated with Chemotherapy and Surgical Resection Leading to Prolonged Survival with No RecurrenceMasato Yasui0Ryosuke Jikuya1Tomoyuki Tatenuma2Kentaro Muraoka3Susumu Umemoto4Masaki Kawai5Tsutomu Kouno6Takeshi Kishida7Department of Urology, Kanagawa Cancer Center, Yokohama, JapanDepartment of Urology, Kanagawa Cancer Center, Yokohama, JapanDepartment of Urology, Kanagawa Cancer Center, Yokohama, JapanDepartment of Urology, Kanagawa Cancer Center, Yokohama, JapanDepartment of Urology, Kanagawa Cancer Center, Yokohama, JapanDepartment of Urology, Kanagawa Cancer Center, Yokohama, JapanDepartment of Medical Oncology, Sasaki Foundation Kyoundo Hospital, Tokyo, JapanDepartment of Urology, Kanagawa Cancer Center, Yokohama, JapanA 56-year-old man was admitted to our hospital for urachal carcinoma with peritoneal dissemination. He received first-line chemotherapy with gemcitabine and cisplatin. After the fifth cycle, a computed tomography (CT) scan revealed abdominal fluid, and his serum tumor marker levels were increased. The patient was started on second-line therapy with FOLFIRI. After 11 cycles, his tumor decreased in size and no new metastatic lesions were detected. The patient underwent complete tumor resection with partial cystectomy and pelvic lymph node dissection. The tumor was removed, along with adhering surrounding organs, including the omentum, peritoneum, abdominal rectus muscle, and vermiform appendix. Although pathological examination confirmed peritoneal dissemination, his tumor markers normalized soon after surgery. The patient has survived 62 months after surgery without any adjuvant therapy and with no evidence of recurrence. To our knowledge, this is the longest duration of survival without recurrence of a patient with urachal carcinoma with peritoneal dissemination who received multimodal therapy.http://dx.doi.org/10.1155/2018/9836154 |
| spellingShingle | Masato Yasui Ryosuke Jikuya Tomoyuki Tatenuma Kentaro Muraoka Susumu Umemoto Masaki Kawai Tsutomu Kouno Takeshi Kishida Urachal Carcinoma with Peritoneal Dissemination Treated with Chemotherapy and Surgical Resection Leading to Prolonged Survival with No Recurrence Case Reports in Urology |
| title | Urachal Carcinoma with Peritoneal Dissemination Treated with Chemotherapy and Surgical Resection Leading to Prolonged Survival with No Recurrence |
| title_full | Urachal Carcinoma with Peritoneal Dissemination Treated with Chemotherapy and Surgical Resection Leading to Prolonged Survival with No Recurrence |
| title_fullStr | Urachal Carcinoma with Peritoneal Dissemination Treated with Chemotherapy and Surgical Resection Leading to Prolonged Survival with No Recurrence |
| title_full_unstemmed | Urachal Carcinoma with Peritoneal Dissemination Treated with Chemotherapy and Surgical Resection Leading to Prolonged Survival with No Recurrence |
| title_short | Urachal Carcinoma with Peritoneal Dissemination Treated with Chemotherapy and Surgical Resection Leading to Prolonged Survival with No Recurrence |
| title_sort | urachal carcinoma with peritoneal dissemination treated with chemotherapy and surgical resection leading to prolonged survival with no recurrence |
| url | http://dx.doi.org/10.1155/2018/9836154 |
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