Renal Cell Carcinoma in the Background of Autosomal Dominant Polycystic Kidney Disease: Report of Two Cases and Review of Literature

Renal Cell Carcinoma in the Background of Autosomal Dominant Polycystic Kidney Disease: Report of Two Cases and Review of Literature

Patients with autosomal dominant polycystic kidney disease (ADPKD), especially those with renal failure, carry a higher risk of developing renal cell carcinoma (RCC) compared to the general population. Genetic mutations associated with ADPKD are known but a direct link associated with RCC is still c...

Full description

Saved in:

Bibliographic Details
Main Authors:	Poorva Vias, Shikha Goyal, Renu Madan, Nandita Kakkar, Ridhi Sood, Kannan Periasamy, Rajender Kumar
Format:	Article
Language:	English
Published:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2024-04-01
Series:	Indian Journal of Medical and Paediatric Oncology
Subjects:	autosomal dominant polycystic kidney disease tubulocystic renal cell carcinoma papillary renal cell carcinoma mTOR inhibitors sunitinib
Online Access:	http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-57268
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Incidental finding of probable epididymal adenomatoid tumor and tubulocystic renal cell carcinoma in a patient with epididymo-orchitis: a case report
by: Alexandra Ghadieh, et al.
Published: (2025-03-01)

Managing metastatic renal cell carcinoma-challenges, pitfalls, and outcomes in the real world
by: Karnam Ashok Kumar, et al.
Published: (2016-01-01)

Case Report: Papillary renal cell carcinoma complicated by ipsilateral renal tuberculosis
by: Zhong Tian, et al.
Published: (2025-08-01)

Understanding Treatment Decisions and Management for Patients with Advanced Renal Cell Carcinoma Using Hypothetical Case Studies: A Vodcast
by: Benjamin Garmezy, et al.
Published: (2024-10-01)

Extensive genotype-phenotype heterogeneity in renal cell carcinoma - a proof-of-concept study
by: Jakob Wieke, et al.
Published: (2025-04-01)

Baicalin reduces sunitinib-induced cardiotoxicity in renal carcinoma PDX model by inhibiting myocardial injury, apoptosis and fibrosis
by: Zefu Yang, et al.
Published: (2025-04-01)

Efficacy of cabozantinib and sunitinib for the treatment of intermediate/poor risk renal cell carcinoma based upon UK real-world data
by: D. Lee, et al.
Published: (2024-12-01)

CYP1B1 promotes angiogenesis and sunitinib resistance in clear cell renal cell carcinoma via USP5-mediated HIF2α deubiquitination
by: Ke Ma, et al.
Published: (2025-08-01)

Protein kinase CK2 sustains de novo fatty acid synthesis by regulating the expression of SCD-1 in human renal cancer cells
by: Barbara Guerra, et al.
Published: (2024-12-01)

Clear Cell Papillary Renal Cell Carcinoma Incidentally Discovered in a Patient With Normal Renal Function: A Case Report
by: Toru Inoue, et al.
Published: (2025-07-01)

Sunitinib and Reversible Posterior Leukoencephalopathy Syndrome: the usual suspect but not always the culprit. A case report.
by: Katopodis Ourania, et al.
Published: (2025-04-01)

Clinical and molecular prognostic nomograms for patients with papillary renal cell carcinoma
by: Xuhui Wang
Published: (2024-12-01)

Resveratrol liposomes reverse sorafenib resistance in renal cell carcinoma models by modulating PI3K-AKT-mTOR and VHL-HIF signaling pathways
by: Ligang Wang, et al.
Published: (2024-12-01)

TRIP13-induced NUSAP1 upregulation promotes CcRCC progression through EMT and PI3K/AKT/mTOR pathway
by: Xiaolong Chen, et al.
Published: (2025-08-01)

Determining the Impact of Histology on the Incidence, Pattern, and Timing of Recurrences in Patients with Renal Cell Carcinoma: A Pooled Analysis from the SORCE and ASSURE Trials
by: Bhavna Oza, et al.
Published: (2025-09-01)

Impact of first-line tyrosine kinase inhibitor selection on survival outcomes with second-line nivolumab in metastatic renal cell carcinoma
by: Omer Faruk Kuzu, et al.
Published: (2025-07-01)

Multimodality Imaging Features of Papillary Renal Cell Carcinoma
by: Rosita Comune, et al.
Published: (2025-04-01)

Novel Therapeutic Strategies Targeting Molecular Pathways of Cystogenesis in Autosomal Polycystic Kidney Disease
by: Maurizio Salvadori, et al.
Published: (2017-03-01)

Autophagy inhibition potentiates anti-cancer activity of Sunitinib in kidney cancer cells
by: Simone Patergnani, et al.
Published: (2025-07-01)

Cáncer Renal Hereditario Bilateral en Von Hippel Lindau.
by: Pablo Le Masson T., et al.
Published: (2020-12-01)

Stereotactic Ablative Radiation Therapy for Metastatic Renal Cell Carcinoma – A Review of Evidence
by: Hima Bora, et al.
Published: (2025-04-01)

Histopathological pattern of adult renal tumours in a tertiary cancer center
by: Ranjan Bhatta, et al.
Published: (2022-03-01)

Periosteum-derived mesenchymal stem cell alleviates renal fibrosis through mTOR-mediated Treg differentiation
by: Yongsheng Luo, et al.
Published: (2023-12-01)

The relationship between renal cell carcinoma pathological types and perirenal fat area
by: Xin Leng, et al.
Published: (2025-05-01)

Genetics and Tumor Microenvironment of Renal Cell Carcinoma
by: Sari Khaleel, et al.
Published: (2022-11-01)

Peroxidasin expression is increased in intratumoural capillaries and in proximal tubular cells adjacent to clear cell renal cell carcinoma.
by: Roberto Silva, et al.
Published: (2025-09-01)

POSSIBILITIES OF ORGAN-PRESERVING TREATMENT OF PATIENTS WITH MULTIPLE RENAL TUMORS
by: B. Ya. Alekseev, et al.
Published: (2017-06-01)

MiT family translocation-associated renal cell carcinoma: A report of two cases in children
by: Sriranjan Mukherjee, et al.
Published: (2024-04-01)

Nivolumab plus cabozantinib in metastatic renal cell carcinoma: real-world evidence from the international ARON-1 study
by: Maria T. Bourlon, et al.
Published: (2025-07-01)

Renal cell carcinoma in a cow
by: Zabid Yener

Diagnosis of Hereditary Leiomyomatosis and Renal Cell Cancer After Subcapsular Renal Hematoma
by: Kazuma Soya, et al.
Published: (2025-05-01)

Genome-wide CRISPR/Cas9 screening identifies PTGR2 as a potential therapeutic target for sunitinib resistance in clear cell renal cell carcinoma
by: Wei Chang, et al.
Published: (2025-07-01)

Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma
by: Liuyan Chen, et al.
Published: (2025-01-01)

Long-term survival with multidisciplinary treatment in metastatic sarcomatoid renal cell carcinoma: a case report and literature review
by: Xin Li, et al.
Published: (2025-08-01)

Prostatic cyst in autosomal recessive polycystic kidney disease: A case presentation and literature review
by: Ketty Bai, et al.
Published: (2024-11-01)

Aminophylline suppresses chronic renal failure progression by activating SIRT1/AMPK/mTOR-dependent autophagy
by: Liao Xin, et al.
Published: (2024-05-01)

Renal Cell Carcinoma With Intratumoral Pseudoaneurysm
by: Daniel P. Pierce, et al.
Published: (2022-11-01)

Comparison of Outcomes Between Radical Nephrectomy and Partial Nephrectomy in Clinical T2 Renal Cell Carcinoma: A Retrospective Korean Renal Cell Carcinoma Cohort Study
by: Younsoo Chung, et al.
Published: (2024-07-01)

Special pathological type of upper urinary tract malignancy—squamous cell carcinoma of the renal pelvis: A case report and literature review
by: Xiaodong Zhu, et al.
Published: (2025-03-01)

Synchronous papillary renal neoplasm with reverse polarity and membranous nephropathy: a rare case report
by: Qingfei Xing, et al.
Published: (2025-05-01)