Rotavirus vaccine coverage, completion, and compliance: A systematic literature review
Rotavirus, a leading cause of severe acute gastroenteritis in children, is largely preventable through immunization with two internationally licensed oral rotavirus vaccines (RVVs) included in national programs across over 100 countries. These RVVs are administered in either two (Rotarix™; 2D-RV) or...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Human Vaccines & Immunotherapeutics |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/21645515.2024.2442780 |
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| _version_ | 1841560773631934464 |
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| author | Halima Tahrat Ali Munir Federico Marchetti |
| author_facet | Halima Tahrat Ali Munir Federico Marchetti |
| author_sort | Halima Tahrat |
| collection | DOAJ |
| description | Rotavirus, a leading cause of severe acute gastroenteritis in children, is largely preventable through immunization with two internationally licensed oral rotavirus vaccines (RVVs) included in national programs across over 100 countries. These RVVs are administered in either two (Rotarix™; 2D-RV) or three (RotaTeq®; 3D-RV) doses. We aimed to assess the global coverage, completion, and compliance of 2D-RV and 3D-RV in various settings, and to identify factors influencing vaccine coverage. We conducted a systematic review of PubMed and Embase for articles published between 2006 and 2021. We included 74 publications across 31 countries. RVV coverage rates and the factors associated with coverage varied widely among countries based on income level, RVV used, and the year of vaccination. Due to market bias and insufficient studies, valid RVVs coverage comparisons couldn’t be made. However, 2D-RV had better completion/compliance rates than 3D-RV in Italy, Mexico, and the US. |
| format | Article |
| id | doaj-art-5a878821d92b46d8aa5435dd327a695a |
| institution | Kabale University |
| issn | 2164-5515 2164-554X |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj-art-5a878821d92b46d8aa5435dd327a695a2025-01-03T15:24:18ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2025-12-0121110.1080/21645515.2024.2442780Rotavirus vaccine coverage, completion, and compliance: A systematic literature reviewHalima Tahrat0Ali Munir1Federico Marchetti2GSK, Rockville, MD, USAGSK, Wavre, BelgiumGSK, Verona, ItalyRotavirus, a leading cause of severe acute gastroenteritis in children, is largely preventable through immunization with two internationally licensed oral rotavirus vaccines (RVVs) included in national programs across over 100 countries. These RVVs are administered in either two (Rotarix™; 2D-RV) or three (RotaTeq®; 3D-RV) doses. We aimed to assess the global coverage, completion, and compliance of 2D-RV and 3D-RV in various settings, and to identify factors influencing vaccine coverage. We conducted a systematic review of PubMed and Embase for articles published between 2006 and 2021. We included 74 publications across 31 countries. RVV coverage rates and the factors associated with coverage varied widely among countries based on income level, RVV used, and the year of vaccination. Due to market bias and insufficient studies, valid RVVs coverage comparisons couldn’t be made. However, 2D-RV had better completion/compliance rates than 3D-RV in Italy, Mexico, and the US.https://www.tandfonline.com/doi/10.1080/21645515.2024.2442780Rotavirusnational immunization programcoveragecompletioncompliancegastroenteritis |
| spellingShingle | Halima Tahrat Ali Munir Federico Marchetti Rotavirus vaccine coverage, completion, and compliance: A systematic literature review Human Vaccines & Immunotherapeutics Rotavirus national immunization program coverage completion compliance gastroenteritis |
| title | Rotavirus vaccine coverage, completion, and compliance: A systematic literature review |
| title_full | Rotavirus vaccine coverage, completion, and compliance: A systematic literature review |
| title_fullStr | Rotavirus vaccine coverage, completion, and compliance: A systematic literature review |
| title_full_unstemmed | Rotavirus vaccine coverage, completion, and compliance: A systematic literature review |
| title_short | Rotavirus vaccine coverage, completion, and compliance: A systematic literature review |
| title_sort | rotavirus vaccine coverage completion and compliance a systematic literature review |
| topic | Rotavirus national immunization program coverage completion compliance gastroenteritis |
| url | https://www.tandfonline.com/doi/10.1080/21645515.2024.2442780 |
| work_keys_str_mv | AT halimatahrat rotavirusvaccinecoveragecompletionandcomplianceasystematicliteraturereview AT alimunir rotavirusvaccinecoveragecompletionandcomplianceasystematicliteraturereview AT federicomarchetti rotavirusvaccinecoveragecompletionandcomplianceasystematicliteraturereview |