A Rare Cause of Reversible Renal Hemosiderosis

Kidney failure secondary to renal hemosiderosis has been reported in diseases with intravascular hemolysis, like paroxysmal nocturnal hemoglobinuria, and valvular heart diseases. We present here a case of hemosiderin induced acute tubular necrosis secondary to intravascular hemolysis from Clostridiu...

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Main Authors: Rima Abou Arkoub, Don Wang, Deborah Zimmerman
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2015/464059
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author Rima Abou Arkoub
Don Wang
Deborah Zimmerman
author_facet Rima Abou Arkoub
Don Wang
Deborah Zimmerman
author_sort Rima Abou Arkoub
collection DOAJ
description Kidney failure secondary to renal hemosiderosis has been reported in diseases with intravascular hemolysis, like paroxysmal nocturnal hemoglobinuria, and valvular heart diseases. We present here a case of hemosiderin induced acute tubular necrosis secondary to intravascular hemolysis from Clostridium difficile infection with possible role of supratherapeutic INR. We discuss the pathophysiology, causes, and prognosis of acute tubular injury from hemosiderosis.
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spelling doaj-art-5a785eb7e5ba4e49a1401614bd4358e42025-02-03T00:59:50ZengWileyCase Reports in Nephrology2090-66412090-665X2015-01-01201510.1155/2015/464059464059A Rare Cause of Reversible Renal HemosiderosisRima Abou Arkoub0Don Wang1Deborah Zimmerman2Division of nephrology, The Ottawa Hospital, Ottawa, ON, K1H 7W9, CanadaDivision of Anatomical Pathology, Department of Pathology and Laboratory Medicine, The Ottawa Hospital and Kidney Research Centre of the Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, K1H 7W9, CanadaDivision of Nephrology, The Ottawa Hospital and University of Ottawa, Ottawa, ON, K1H 7W9, CanadaKidney failure secondary to renal hemosiderosis has been reported in diseases with intravascular hemolysis, like paroxysmal nocturnal hemoglobinuria, and valvular heart diseases. We present here a case of hemosiderin induced acute tubular necrosis secondary to intravascular hemolysis from Clostridium difficile infection with possible role of supratherapeutic INR. We discuss the pathophysiology, causes, and prognosis of acute tubular injury from hemosiderosis.http://dx.doi.org/10.1155/2015/464059
spellingShingle Rima Abou Arkoub
Don Wang
Deborah Zimmerman
A Rare Cause of Reversible Renal Hemosiderosis
Case Reports in Nephrology
title A Rare Cause of Reversible Renal Hemosiderosis
title_full A Rare Cause of Reversible Renal Hemosiderosis
title_fullStr A Rare Cause of Reversible Renal Hemosiderosis
title_full_unstemmed A Rare Cause of Reversible Renal Hemosiderosis
title_short A Rare Cause of Reversible Renal Hemosiderosis
title_sort rare cause of reversible renal hemosiderosis
url http://dx.doi.org/10.1155/2015/464059
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