Rotavirus-Specific Maternal Serum Antibodies and Vaccine Responses to RV3-BB Rotavirus Vaccine Administered in a Neonatal or Infant Schedule in Malawi

Rotavirus-Specific Maternal Serum Antibodies and Vaccine Responses to RV3-BB Rotavirus Vaccine Administered in a Neonatal or Infant Schedule in Malawi

High titres of rotavirus-specific maternal antibodies may contribute to lower rotavirus vaccine efficacy in low- and middle-income countries (LMICs). RV3-BB vaccine (G3P[6]) is based on a neonatal rotavirus strain that replicates well in the newborn gut in the presence of breast milk. This study inv...

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Bibliographic Details
Main Authors: Benjamin Morgan, Eleanor A. Lyons, Amanda Handley, Nada Bogdanovic-Sakran, Daniel Pavlic, Desiree Witte, Jonathan Mandolo, Ann Turner, Khuzwayo C. Jere, Frances Justice, Darren Suryawijaya Ong, Rhian Bonnici, Karen Boniface, Celeste M. Donato, Ashley Mpakiza, Anell Meyer, Naor Bar-Zeev, Miren Iturriza-Gomara, Nigel A. Cunliffe, Margaret Danchin, Julie E. Bines
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Viruses
Subjects:
rotavirus vaccine
maternal antibodies
RV3-BB vaccine
Online Access:https://www.mdpi.com/1999-4915/16/9/1488
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