Sticky Platelet Syndrome as a Cause of Recurrent Miscarriages: A Rare Case Report
Sticky platelet syndrome (SPS) is a hereditary disorder. SPS can cause pregnancy complications, such as recurrent miscarriages. However, proper management can prevent the incidence of recurrent miscarriages. Here, we describe a case of a woman who lost her fifth first-trimester pregnancy, and upon...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2025-04-01
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| Series: | Acta Medica Indonesiana |
| Online Access: | http://www.actamedindones.org/index.php/ijim/article/view/2658 |
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| author | Dedy Kristofer Simangunsong Alvina Widhani Ardhi Rahman Ahani Eirene Simbolon Hadiki Habib |
| author_facet | Dedy Kristofer Simangunsong Alvina Widhani Ardhi Rahman Ahani Eirene Simbolon Hadiki Habib |
| author_sort | Dedy Kristofer Simangunsong |
| collection | DOAJ |
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Sticky platelet syndrome (SPS) is a hereditary disorder. SPS can cause pregnancy complications, such as recurrent miscarriages. However, proper management can prevent the incidence of recurrent miscarriages. Here, we describe a case of a woman who lost her fifth first-trimester pregnancy, and upon assessment, we discovered SPS. The 33-year-old woman underwent consultation with an obstetrician because of her history of five first-semester miscarriages. Gynecology ultrasound, infection parameters, hormonal and metabolic panels, and autoimmune workup were all found to be normal; however, vitamin D deficiency was identified as was SPS from a platelet aggregation test. The patient was then treated with clopidogrel and vitamin D3 supplementation. She became pregnant after five months of treatment. Her pregnancy was normal and she went into delivery at 40 weeks gestation with no maternal or fetal complications.
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| format | Article |
| id | doaj-art-5a72acc43f6e4e3a8a9c21120afe437f |
| institution | OA Journals |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-5a72acc43f6e4e3a8a9c21120afe437f2025-08-20T02:37:17ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322025-04-01571Sticky Platelet Syndrome as a Cause of Recurrent Miscarriages: A Rare Case ReportDedy Kristofer Simangunsong0Alvina Widhani1Ardhi Rahman Ahani2Eirene Simbolon3Hadiki Habib4Cipto Mangunkusumo Hospital, Jakarta, IndonesiaDivision of Allergy and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, IndonesiaDivision of Hematology and Clinical Oncology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, IndonesiaNational Sports Hospital, Jakarta, Indonesia1. Division of Respirology and Critical Care, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia. 2. Emergency Unit, Cipto Mangunkusumo Hospital, Jakarta, Indonesia Sticky platelet syndrome (SPS) is a hereditary disorder. SPS can cause pregnancy complications, such as recurrent miscarriages. However, proper management can prevent the incidence of recurrent miscarriages. Here, we describe a case of a woman who lost her fifth first-trimester pregnancy, and upon assessment, we discovered SPS. The 33-year-old woman underwent consultation with an obstetrician because of her history of five first-semester miscarriages. Gynecology ultrasound, infection parameters, hormonal and metabolic panels, and autoimmune workup were all found to be normal; however, vitamin D deficiency was identified as was SPS from a platelet aggregation test. The patient was then treated with clopidogrel and vitamin D3 supplementation. She became pregnant after five months of treatment. Her pregnancy was normal and she went into delivery at 40 weeks gestation with no maternal or fetal complications. http://www.actamedindones.org/index.php/ijim/article/view/2658 |
| spellingShingle | Dedy Kristofer Simangunsong Alvina Widhani Ardhi Rahman Ahani Eirene Simbolon Hadiki Habib Sticky Platelet Syndrome as a Cause of Recurrent Miscarriages: A Rare Case Report Acta Medica Indonesiana |
| title | Sticky Platelet Syndrome as a Cause of Recurrent Miscarriages: A Rare Case Report |
| title_full | Sticky Platelet Syndrome as a Cause of Recurrent Miscarriages: A Rare Case Report |
| title_fullStr | Sticky Platelet Syndrome as a Cause of Recurrent Miscarriages: A Rare Case Report |
| title_full_unstemmed | Sticky Platelet Syndrome as a Cause of Recurrent Miscarriages: A Rare Case Report |
| title_short | Sticky Platelet Syndrome as a Cause of Recurrent Miscarriages: A Rare Case Report |
| title_sort | sticky platelet syndrome as a cause of recurrent miscarriages a rare case report |
| url | http://www.actamedindones.org/index.php/ijim/article/view/2658 |
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