The hepatic transcriptome is differentially regulated by a standardized meal in healthy individuals compared to patients with fatty liver disease.

The human liver is dynamic organ with minute to hourly adaptions in response to feeding. Patients with non-alcoholic fatty liver disease (NAFLD) and cirrhosis have altered transcriptomic features compared to controls but how and if food intake affects such is unknown in humans. Our aim was to invest...

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Main Authors: Josephine Grandt, Christian D Johansen, Anne-Sofie H Jensen, Mikkel P Werge, Elias B Rashu, Andreas Møller, Anders E Junker, Lise Hobolth, Christian Mortensen, Mogens Vyberg, Reza Rafiolsadat Serizawa, Søren Møller, Lise Lotte Gluud, Nicolai J Wewer Albrechtsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0307345
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