Compartmentalised mucosal and blood immunity to SARS-CoV-2 is associated with high seroprevalence before the Delta wave in Africa

Compartmentalised mucosal and blood immunity to SARS-CoV-2 is associated with high seroprevalence before the Delta wave in Africa

Abstract Background The reported number of SARS-CoV-2 cases and deaths are lower in Africa compared to many high-income countries. However, in African cohorts, detailed characterisation of SARS-CoV-2 mucosal and T cell immunity are limited. We assessed the SARS-CoV-2-specific immune landscape in The...

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Main Authors: Ya Jankey Jagne, Dawda Jobe, Alansana Darboe, Madikoi Danso, Natalie Barratt, Marie Gomez, Rhys Wenlock, Sheikh Jarju, Ellen Lena Sylva, Aji Fatou Touray, Fatoumata Toure, Michelle Kumado, Anja Saso, Domen Zafred, Martin Nicklin, Jon Sayers, Hailey Hornsby, Benjamin Lindsey, Abdul Karim Sesay, Nigel Temperton, Adam Kucharski, David Hodgson, Thushan de Silva, Beate Kampmann
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00902-x
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