Inhibitors of the interferon response enhance virus replication in vitro.

Inhibitors of the interferon response enhance virus replication in vitro.

Virus replication efficiency is influenced by two conflicting factors, kinetics of the cellular interferon (IFN) response and induction of an antiviral state versus speed of virus replication and virus-induced inhibition of the IFN response. Disablement of a virus's capacity to circumvent the I...

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Bibliographic Details
Main Authors: Claire E Stewart, Richard E Randall, Catherine S Adamson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0112014
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