Thiostrepton induces apoptotic cell death at the level of BCL-2/CED-9 in C. elegans
Abstract Thiostrepton, a thiopeptide antibiotic, has been attracting increasing attention for its anti-proliferative and anti-cancer properties in various tested cell culture models. Extensive in vitro analysis has been conducted to understand its anti-cancer effect across multiple cancer types and...
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| Main Authors: | Alanoud Al-Kaabi, Tayyiba Akbar Ali, Mahmoud Izadi, Kirti S. Prabhu, Shahab Uddin, Ehsan Pourkarimi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-09446-5 |
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