Thiostrepton induces apoptotic cell death at the level of BCL-2/CED-9 in C. elegans

Abstract Thiostrepton, a thiopeptide antibiotic, has been attracting increasing attention for its anti-proliferative and anti-cancer properties in various tested cell culture models. Extensive in vitro analysis has been conducted to understand its anti-cancer effect across multiple cancer types and...

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Bibliographic Details
Main Authors: Alanoud Al-Kaabi, Tayyiba Akbar Ali, Mahmoud Izadi, Kirti S. Prabhu, Shahab Uddin, Ehsan Pourkarimi
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-09446-5
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