Identification of a T1D Susceptibility Gene

It is not known what causes type 1 diabetes (T1D), which affects over 1 million people in the U.S. alone. Each year, 30,000 young people in the U.S. develop this disease and depend on insulin injections thereafter. Because of the huge cost to the individual, the family, and to society in increased h...

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Main Author: Grant Morahan
Format: Article
Language:English
Published: Wiley 2001-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2001.30
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author Grant Morahan
author_facet Grant Morahan
author_sort Grant Morahan
collection DOAJ
description It is not known what causes type 1 diabetes (T1D), which affects over 1 million people in the U.S. alone. Each year, 30,000 young people in the U.S. develop this disease and depend on insulin injections thereafter. Because of the huge cost to the individual, the family, and to society in increased health care costs, it is important to find what makes these people susceptible. The disease process itself is clear: the individual’s immune system — T lymphocytes in particular — attack and destroy the body’s insulin-producing cells. But how and why this autoimmune process starts or proceeds unregulated is still not known.
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spelling doaj-art-5a442b9f0ada4aa4990b57f4eafe32a62025-08-20T03:34:40ZengWileyThe Scientific World Journal1537-744X2001-01-01119819910.1100/tsw.2001.30Identification of a T1D Susceptibility GeneGrant Morahan0Complex Genetic Diseases Laboratoty, The Walter and Eliza Hall Institute of Medical Research, PO Royal Melbourne Hospital, Victoria, AustraliaIt is not known what causes type 1 diabetes (T1D), which affects over 1 million people in the U.S. alone. Each year, 30,000 young people in the U.S. develop this disease and depend on insulin injections thereafter. Because of the huge cost to the individual, the family, and to society in increased health care costs, it is important to find what makes these people susceptible. The disease process itself is clear: the individual’s immune system — T lymphocytes in particular — attack and destroy the body’s insulin-producing cells. But how and why this autoimmune process starts or proceeds unregulated is still not known.http://dx.doi.org/10.1100/tsw.2001.30
spellingShingle Grant Morahan
Identification of a T1D Susceptibility Gene
The Scientific World Journal
title Identification of a T1D Susceptibility Gene
title_full Identification of a T1D Susceptibility Gene
title_fullStr Identification of a T1D Susceptibility Gene
title_full_unstemmed Identification of a T1D Susceptibility Gene
title_short Identification of a T1D Susceptibility Gene
title_sort identification of a t1d susceptibility gene
url http://dx.doi.org/10.1100/tsw.2001.30
work_keys_str_mv AT grantmorahan identificationofat1dsusceptibilitygene