Asian flushing, ADH1B, aldehyde dehydrogenase 2 genotypic status among the unique ethnic population of the Himalayan state of Sikkim, India

Asian flushing, ADH1B, aldehyde dehydrogenase 2 genotypic status among the unique ethnic population of the Himalayan state of Sikkim, India

Background: Alcohol induced flushing a phenotypic instrument variable also known as “Asian flush” was first reported by Wolff (1972), commonly seen among East Asians. This phenotype is indicative of inactive aldehyde dehydrogenase 2 (ALDH2) and high activity of alcohol dehydrogenase (ADH1B). Aims...

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Bibliographic Details
Main Authors: Yazum Bhutia, Sanjiba Dutta, Mingma Lhamu Sherpa
Format: Article
Language:English
Published: Manipal College of Medical Sciences, Pokhara 2024-12-01
Series:Asian Journal of Medical Sciences
Subjects:
adh1b; aldehyde dehydrogenase 2; alcohol induced flushing; sensitivity; specificity
sikkim
Online Access:https://www.nepjol.info/index.php/AJMS/article/view/70143
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