OXA-type carbapenemases in Acinetobacter baumannii in South America
Acinetobacter baumannii is an opportunistic pathogen that is frequently involved in outbreaks of infection, occurring mostly in intensive care units. The increasing incidence of carbapenem resistance in A. baumannii worldwide is a concern since it limits drastically the range of therapeutic alterna...
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| Format: | Article |
| Language: | English |
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The Journal of Infection in Developing Countries
2011-12-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/2310 |
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| author | Andrés Opazo Mariana Domínguez Helia Bello Sebastian G.B. Amyes Gerardo González-Rocha |
| author_facet | Andrés Opazo Mariana Domínguez Helia Bello Sebastian G.B. Amyes Gerardo González-Rocha |
| author_sort | Andrés Opazo |
| collection | DOAJ |
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Acinetobacter baumannii is an opportunistic pathogen that is frequently involved in outbreaks of infection, occurring mostly in intensive care units. The increasing incidence of carbapenem resistance in A. baumannii worldwide is a concern since it limits drastically the range of therapeutic alternatives. The most important mechanism of carbapenem resistance is the enzymatic hydrolysis mediated by carbapenemases. In A. baumannii these enzymes are usually OXA-type carbapenemases, and belong to class D according to the classification of Ambler. The OXA-type carbapenemases are divided into five subgroups, four of which correspond to acquired carbapenemases, which accounts for the distribution of genes blaOXA in different geographic areas. In this work we review the different types of OXA-type carbapenemases present in A. baumannii, emphasizing the current situation in South America with special mention to the findings in Chile.
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| format | Article |
| id | doaj-art-5a275c45dd9e409ea50238a04777eb03 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2011-12-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-5a275c45dd9e409ea50238a04777eb032025-08-20T02:16:06ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802011-12-0160410.3855/jidc.2310OXA-type carbapenemases in Acinetobacter baumannii in South AmericaAndrés Opazo0Mariana Domínguez1Helia Bello2Sebastian G.B. Amyes3Gerardo González-Rocha4Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, ChileFacultad de Ciencias Biológicas, Universidad de Concepción, Concepción, ChileFacultad de Ciencias Biológicas, Universidad de Concepción, Concepción, ChileMolecular Chemotherapy, Centre for Infectious Diseases, University of Edinburgh, Edinburgh, United KingdomFacultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile Acinetobacter baumannii is an opportunistic pathogen that is frequently involved in outbreaks of infection, occurring mostly in intensive care units. The increasing incidence of carbapenem resistance in A. baumannii worldwide is a concern since it limits drastically the range of therapeutic alternatives. The most important mechanism of carbapenem resistance is the enzymatic hydrolysis mediated by carbapenemases. In A. baumannii these enzymes are usually OXA-type carbapenemases, and belong to class D according to the classification of Ambler. The OXA-type carbapenemases are divided into five subgroups, four of which correspond to acquired carbapenemases, which accounts for the distribution of genes blaOXA in different geographic areas. In this work we review the different types of OXA-type carbapenemases present in A. baumannii, emphasizing the current situation in South America with special mention to the findings in Chile. https://jidc.org/index.php/journal/article/view/2310Acinetobacter baumanniicarbapenem-resistanceOXA-type carbapenemasesSouth AmericaChile |
| spellingShingle | Andrés Opazo Mariana Domínguez Helia Bello Sebastian G.B. Amyes Gerardo González-Rocha OXA-type carbapenemases in Acinetobacter baumannii in South America Journal of Infection in Developing Countries Acinetobacter baumannii carbapenem-resistance OXA-type carbapenemases South America Chile |
| title | OXA-type carbapenemases in Acinetobacter baumannii in South America |
| title_full | OXA-type carbapenemases in Acinetobacter baumannii in South America |
| title_fullStr | OXA-type carbapenemases in Acinetobacter baumannii in South America |
| title_full_unstemmed | OXA-type carbapenemases in Acinetobacter baumannii in South America |
| title_short | OXA-type carbapenemases in Acinetobacter baumannii in South America |
| title_sort | oxa type carbapenemases in acinetobacter baumannii in south america |
| topic | Acinetobacter baumannii carbapenem-resistance OXA-type carbapenemases South America Chile |
| url | https://jidc.org/index.php/journal/article/view/2310 |
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