Acute muscular weakness in children
ABSTRACT Acute muscle weakness in children is a pediatric emergency. During the diagnostic approach, it is crucial to obtain a detailed case history, including: onset of weakness, history of associated febrile states, ingestion of toxic substances/toxins, immunizations, and family history. Neurologi...
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000400248&lng=en&tlng=en |
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| author | Ricardo Pablo Javier Erazo Torricelli |
| author_facet | Ricardo Pablo Javier Erazo Torricelli |
| author_sort | Ricardo Pablo Javier Erazo Torricelli |
| collection | DOAJ |
| description | ABSTRACT Acute muscle weakness in children is a pediatric emergency. During the diagnostic approach, it is crucial to obtain a detailed case history, including: onset of weakness, history of associated febrile states, ingestion of toxic substances/toxins, immunizations, and family history. Neurological examination must be meticulous as well. In this review, we describe the most common diseases related to acute muscle weakness, grouped into the site of origin (from the upper motor neuron to the motor unit). Early detection of hyperCKemia may lead to a myositis diagnosis, and hypokalemia points to the diagnosis of periodic paralysis. Ophthalmoparesis, ptosis and bulbar signs are suggestive of myasthenia gravis or botulism. Distal weakness and hyporeflexia are clinical features of Guillain-Barré syndrome, the most frequent cause of acute muscle weakness. If all studies are normal, a psychogenic cause should be considered. Finding the etiology of acute muscle weakness is essential to execute treatment in a timely manner, improving the prognosis of affected children. |
| format | Article |
| id | doaj-art-5a2285af375647748bfcd4e2a2d45f6a |
| institution | DOAJ |
| issn | 1678-4227 |
| language | English |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-5a2285af375647748bfcd4e2a2d45f6a2025-08-20T03:19:21ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-422775424825410.1590/0004-282x20170026S0004-282X2017000400248Acute muscular weakness in childrenRicardo Pablo Javier Erazo TorricelliABSTRACT Acute muscle weakness in children is a pediatric emergency. During the diagnostic approach, it is crucial to obtain a detailed case history, including: onset of weakness, history of associated febrile states, ingestion of toxic substances/toxins, immunizations, and family history. Neurological examination must be meticulous as well. In this review, we describe the most common diseases related to acute muscle weakness, grouped into the site of origin (from the upper motor neuron to the motor unit). Early detection of hyperCKemia may lead to a myositis diagnosis, and hypokalemia points to the diagnosis of periodic paralysis. Ophthalmoparesis, ptosis and bulbar signs are suggestive of myasthenia gravis or botulism. Distal weakness and hyporeflexia are clinical features of Guillain-Barré syndrome, the most frequent cause of acute muscle weakness. If all studies are normal, a psychogenic cause should be considered. Finding the etiology of acute muscle weakness is essential to execute treatment in a timely manner, improving the prognosis of affected children.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000400248&lng=en&tlng=endebilidade muscularpoliomielitesíndrome de Guillain-Barrébotulismomiastenia gravis |
| spellingShingle | Ricardo Pablo Javier Erazo Torricelli Acute muscular weakness in children Arquivos de Neuro-Psiquiatria debilidade muscular poliomielite síndrome de Guillain-Barré botulismo miastenia gravis |
| title | Acute muscular weakness in children |
| title_full | Acute muscular weakness in children |
| title_fullStr | Acute muscular weakness in children |
| title_full_unstemmed | Acute muscular weakness in children |
| title_short | Acute muscular weakness in children |
| title_sort | acute muscular weakness in children |
| topic | debilidade muscular poliomielite síndrome de Guillain-Barré botulismo miastenia gravis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000400248&lng=en&tlng=en |
| work_keys_str_mv | AT ricardopablojaviererazotorricelli acutemuscularweaknessinchildren |