Pancreatic Perivascular Epithelioid Cell Tumour Presenting with Upper Gastrointestinal Bleeding
PEComa is a family of rare mesenchymal tumours which can occur in any part of the human body. Primary PEComas of the pancreas are extremely rare tumours with uncertain malignant potential. A 17-year-old female was admitted to the hospital due to melena. She required several transfusions. CT scan dem...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/431215 |
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| author | Christos Petrides Kyriakos Neofytou Aamir Z. Khan |
| author_facet | Christos Petrides Kyriakos Neofytou Aamir Z. Khan |
| author_sort | Christos Petrides |
| collection | DOAJ |
| description | PEComa is a family of rare mesenchymal tumours which can occur in any part of the human body. Primary PEComas of the pancreas are extremely rare tumours with uncertain malignant potential. A 17-year-old female was admitted to the hospital due to melena. She required several transfusions. CT scan demonstrated a mass at the head of the pancreas measuring 4.2 cm in maximum diameter. An endoscopic ultrasound showed an ulcerating malignant looking mass infiltrating 50% of the wall of the second part of the duodenum in the region of the ampulla. Multiple biopsies taken showed extensive ulceration with granulation tissue formation and underlying large macrophages without being able to establish a definite diagnosis. We proceeded with pylorus-preserving pancreaticoduodenectomy. The postoperative course of the patient was unremarkable, and she was discharged on the 8th postoperative day. Histology examination of the specimen showed a PEComa of pancreas. Eighteen months after resection the patient is disease free. To the best of our knowledge this is the first time we describe a case of a pancreatic PEComa presenting with massive gastrointestinal bleeding. |
| format | Article |
| id | doaj-art-5a15ff2cc31f4a1cae9cbc3d0671b0d0 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-5a15ff2cc31f4a1cae9cbc3d0671b0d02025-02-03T06:11:48ZengWileyCase Reports in Oncological Medicine2090-67062090-67142015-01-01201510.1155/2015/431215431215Pancreatic Perivascular Epithelioid Cell Tumour Presenting with Upper Gastrointestinal BleedingChristos Petrides0Kyriakos Neofytou1Aamir Z. Khan2Department of Surgery, Nicosia Government Hospital, Palaios Dromos Lefkosias-Lemesou, No. 215, Strovolos, 2029 Nicosia, CyprusDepartment of Academic Surgery, Royal Marsden Hospital, Upper GI/HPB Unit, Fulham Road, London SW3 6JJ, UKDepartment of Academic Surgery, Royal Marsden Hospital, Upper GI/HPB Unit, Fulham Road, London SW3 6JJ, UKPEComa is a family of rare mesenchymal tumours which can occur in any part of the human body. Primary PEComas of the pancreas are extremely rare tumours with uncertain malignant potential. A 17-year-old female was admitted to the hospital due to melena. She required several transfusions. CT scan demonstrated a mass at the head of the pancreas measuring 4.2 cm in maximum diameter. An endoscopic ultrasound showed an ulcerating malignant looking mass infiltrating 50% of the wall of the second part of the duodenum in the region of the ampulla. Multiple biopsies taken showed extensive ulceration with granulation tissue formation and underlying large macrophages without being able to establish a definite diagnosis. We proceeded with pylorus-preserving pancreaticoduodenectomy. The postoperative course of the patient was unremarkable, and she was discharged on the 8th postoperative day. Histology examination of the specimen showed a PEComa of pancreas. Eighteen months after resection the patient is disease free. To the best of our knowledge this is the first time we describe a case of a pancreatic PEComa presenting with massive gastrointestinal bleeding.http://dx.doi.org/10.1155/2015/431215 |
| spellingShingle | Christos Petrides Kyriakos Neofytou Aamir Z. Khan Pancreatic Perivascular Epithelioid Cell Tumour Presenting with Upper Gastrointestinal Bleeding Case Reports in Oncological Medicine |
| title | Pancreatic Perivascular Epithelioid Cell Tumour Presenting with Upper Gastrointestinal Bleeding |
| title_full | Pancreatic Perivascular Epithelioid Cell Tumour Presenting with Upper Gastrointestinal Bleeding |
| title_fullStr | Pancreatic Perivascular Epithelioid Cell Tumour Presenting with Upper Gastrointestinal Bleeding |
| title_full_unstemmed | Pancreatic Perivascular Epithelioid Cell Tumour Presenting with Upper Gastrointestinal Bleeding |
| title_short | Pancreatic Perivascular Epithelioid Cell Tumour Presenting with Upper Gastrointestinal Bleeding |
| title_sort | pancreatic perivascular epithelioid cell tumour presenting with upper gastrointestinal bleeding |
| url | http://dx.doi.org/10.1155/2015/431215 |
| work_keys_str_mv | AT christospetrides pancreaticperivascularepithelioidcelltumourpresentingwithuppergastrointestinalbleeding AT kyriakosneofytou pancreaticperivascularepithelioidcelltumourpresentingwithuppergastrointestinalbleeding AT aamirzkhan pancreaticperivascularepithelioidcelltumourpresentingwithuppergastrointestinalbleeding |