Undifferentiated pleomorphic sarcoma invading thoracic aorta treated by thoracic endovascular aortic repair: a case report
Abstract Background Undifferentiated pleomorphic sarcoma arising from the posterior mediastinum and infiltrating the thoracic aorta is exceptionally rare, with few cases reported in scientific literature. Case presentation A 48-year-old Han Chinese man was admitted with persistent chest pain for 2 m...
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BMC
2025-06-01
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| Series: | Journal of Medical Case Reports |
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| Online Access: | https://doi.org/10.1186/s13256-025-05329-5 |
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| author | Haiyang Li Qihua Gong Wei Wei |
| author_facet | Haiyang Li Qihua Gong Wei Wei |
| author_sort | Haiyang Li |
| collection | DOAJ |
| description | Abstract Background Undifferentiated pleomorphic sarcoma arising from the posterior mediastinum and infiltrating the thoracic aorta is exceptionally rare, with few cases reported in scientific literature. Case presentation A 48-year-old Han Chinese man was admitted with persistent chest pain for 2 months; he had not received a diagnosis or treatment plan from the previous hospital. Firstly, thoracic endovascular aortic repair surgery was performed to safeguard the integrity of the thoracic aorta, followed by a biopsy to confirm undifferentiated pleomorphic sarcoma. A chemotherapy plan was then established on the basis of the latest pathological results. Conclusion Undifferentiated pleomorphic sarcoma is highly malignant, complicating diagnosis and treatment and often resulting in a poor prognosis. Invasion of the posterior mediastinum and aorta is exceptionally rare. An early thoracic endovascular aortic repair intervention to protect the aorta and cut tumor blood supply, followed by needle biopsy for diagnosis, offers an innovative approach that can guide clinical practice. Graphical abstract |
| format | Article |
| id | doaj-art-5a1325fe11de429594a9f3ff96168b68 |
| institution | OA Journals |
| issn | 1752-1947 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj-art-5a1325fe11de429594a9f3ff96168b682025-08-20T02:30:41ZengBMCJournal of Medical Case Reports1752-19472025-06-011911710.1186/s13256-025-05329-5Undifferentiated pleomorphic sarcoma invading thoracic aorta treated by thoracic endovascular aortic repair: a case reportHaiyang Li0Qihua Gong1Wei Wei2Cardiothoracic Surgery Department, Guiqian International General HospitalCardiothoracic Surgery Department, Guiqian International General HospitalCardiothoracic Surgery Department, Guiqian International General HospitalAbstract Background Undifferentiated pleomorphic sarcoma arising from the posterior mediastinum and infiltrating the thoracic aorta is exceptionally rare, with few cases reported in scientific literature. Case presentation A 48-year-old Han Chinese man was admitted with persistent chest pain for 2 months; he had not received a diagnosis or treatment plan from the previous hospital. Firstly, thoracic endovascular aortic repair surgery was performed to safeguard the integrity of the thoracic aorta, followed by a biopsy to confirm undifferentiated pleomorphic sarcoma. A chemotherapy plan was then established on the basis of the latest pathological results. Conclusion Undifferentiated pleomorphic sarcoma is highly malignant, complicating diagnosis and treatment and often resulting in a poor prognosis. Invasion of the posterior mediastinum and aorta is exceptionally rare. An early thoracic endovascular aortic repair intervention to protect the aorta and cut tumor blood supply, followed by needle biopsy for diagnosis, offers an innovative approach that can guide clinical practice. Graphical abstracthttps://doi.org/10.1186/s13256-025-05329-5Undifferentiated pleomorphic sarcoma (UPS)Thoracic aortaThoracic endovascular aortic repair (TEVAR)Case report |
| spellingShingle | Haiyang Li Qihua Gong Wei Wei Undifferentiated pleomorphic sarcoma invading thoracic aorta treated by thoracic endovascular aortic repair: a case report Journal of Medical Case Reports Undifferentiated pleomorphic sarcoma (UPS) Thoracic aorta Thoracic endovascular aortic repair (TEVAR) Case report |
| title | Undifferentiated pleomorphic sarcoma invading thoracic aorta treated by thoracic endovascular aortic repair: a case report |
| title_full | Undifferentiated pleomorphic sarcoma invading thoracic aorta treated by thoracic endovascular aortic repair: a case report |
| title_fullStr | Undifferentiated pleomorphic sarcoma invading thoracic aorta treated by thoracic endovascular aortic repair: a case report |
| title_full_unstemmed | Undifferentiated pleomorphic sarcoma invading thoracic aorta treated by thoracic endovascular aortic repair: a case report |
| title_short | Undifferentiated pleomorphic sarcoma invading thoracic aorta treated by thoracic endovascular aortic repair: a case report |
| title_sort | undifferentiated pleomorphic sarcoma invading thoracic aorta treated by thoracic endovascular aortic repair a case report |
| topic | Undifferentiated pleomorphic sarcoma (UPS) Thoracic aorta Thoracic endovascular aortic repair (TEVAR) Case report |
| url | https://doi.org/10.1186/s13256-025-05329-5 |
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