From Endemic to a Global Concern Once Again: A Review of Evolving Monkeypox Dynamics
The World Health Organization (WHO) declared the ongoing Mpox (formerly known as Monkeypox) outbreak a Public Health Emergency of International Concern (PHEIC) on 14th August 2024, this being the second time, with Mpox previously being declared a PHEIC during the 2022-2023 outbreak. Mpox is a zoono...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
ziauddin University
2025-07-01
|
| Series: | Pakistan Journal of Medicine and Dentistry |
| Subjects: | |
| Online Access: | https://ojs.zu.edu.pk/pjmd/article/view/3581 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849424244292714496 |
|---|---|
| author | Omar Irfan Muskaan Abdul Qadir Aqsa Amjad Mohammad Aadil Qamar Syed Faisal Mahmood |
| author_facet | Omar Irfan Muskaan Abdul Qadir Aqsa Amjad Mohammad Aadil Qamar Syed Faisal Mahmood |
| author_sort | Omar Irfan |
| collection | DOAJ |
| description |
The World Health Organization (WHO) declared the ongoing Mpox (formerly known as Monkeypox) outbreak a Public Health Emergency of International Concern (PHEIC) on 14th August 2024, this being the second time, with Mpox previously being declared a PHEIC during the 2022-2023 outbreak. Mpox is a zoonotic orthopoxvirus with a similar clinical presentation to smallpox but a notably lower mortality rate. Before the 2022 outbreak, Mpox was a rare and neglected disease, which has now drawn global attention once the cases started emerging in countries outside Africa. The WHO has stressed the importance of a coordinated response on the international front to control and contain the Mpox outbreaks in the DRC and neighboring countries in Africa. Through this narrative review, the authors aim to consolidate evidence on the Mpox virus, characteristics of its infection, treatment and prevention strategies, a review of past and current Mpox outbreaks, challenges in containing the spread of the epidemic including access to vaccines in low-income nations and vulnerable populations, and any relevant learnings from the COVID-19 pandemic that could be implemented.
|
| format | Article |
| id | doaj-art-5a12249c82474b3dae62ff2fcdedabf1 |
| institution | Kabale University |
| issn | 2313-7371 2308-2593 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | ziauddin University |
| record_format | Article |
| series | Pakistan Journal of Medicine and Dentistry |
| spelling | doaj-art-5a12249c82474b3dae62ff2fcdedabf12025-08-20T03:30:15Zengziauddin UniversityPakistan Journal of Medicine and Dentistry2313-73712308-25932025-07-0114310.36283/ziun-pjmd14-3/081From Endemic to a Global Concern Once Again: A Review of Evolving Monkeypox DynamicsOmar Irfan0https://orcid.org/0000-0003-0921-1456Muskaan Abdul Qadir1Aqsa Amjad2Mohammad Aadil Qamar3https://orcid.org/0000-0003-3331-6901Syed Faisal Mahmood4https://orcid.org/0000-0002-3390-7659Aga Khan University HospitalAga Khan University HospitalAga Khan University HospitalAga Khan University HospitalAga Khan University Hospital The World Health Organization (WHO) declared the ongoing Mpox (formerly known as Monkeypox) outbreak a Public Health Emergency of International Concern (PHEIC) on 14th August 2024, this being the second time, with Mpox previously being declared a PHEIC during the 2022-2023 outbreak. Mpox is a zoonotic orthopoxvirus with a similar clinical presentation to smallpox but a notably lower mortality rate. Before the 2022 outbreak, Mpox was a rare and neglected disease, which has now drawn global attention once the cases started emerging in countries outside Africa. The WHO has stressed the importance of a coordinated response on the international front to control and contain the Mpox outbreaks in the DRC and neighboring countries in Africa. Through this narrative review, the authors aim to consolidate evidence on the Mpox virus, characteristics of its infection, treatment and prevention strategies, a review of past and current Mpox outbreaks, challenges in containing the spread of the epidemic including access to vaccines in low-income nations and vulnerable populations, and any relevant learnings from the COVID-19 pandemic that could be implemented. https://ojs.zu.edu.pk/pjmd/article/view/3581Monkey poxMpoxOutbreakTransmissionEndemicVirus |
| spellingShingle | Omar Irfan Muskaan Abdul Qadir Aqsa Amjad Mohammad Aadil Qamar Syed Faisal Mahmood From Endemic to a Global Concern Once Again: A Review of Evolving Monkeypox Dynamics Pakistan Journal of Medicine and Dentistry Monkey pox Mpox Outbreak Transmission Endemic Virus |
| title | From Endemic to a Global Concern Once Again: A Review of Evolving Monkeypox Dynamics |
| title_full | From Endemic to a Global Concern Once Again: A Review of Evolving Monkeypox Dynamics |
| title_fullStr | From Endemic to a Global Concern Once Again: A Review of Evolving Monkeypox Dynamics |
| title_full_unstemmed | From Endemic to a Global Concern Once Again: A Review of Evolving Monkeypox Dynamics |
| title_short | From Endemic to a Global Concern Once Again: A Review of Evolving Monkeypox Dynamics |
| title_sort | from endemic to a global concern once again a review of evolving monkeypox dynamics |
| topic | Monkey pox Mpox Outbreak Transmission Endemic Virus |
| url | https://ojs.zu.edu.pk/pjmd/article/view/3581 |
| work_keys_str_mv | AT omarirfan fromendemictoaglobalconcernonceagainareviewofevolvingmonkeypoxdynamics AT muskaanabdulqadir fromendemictoaglobalconcernonceagainareviewofevolvingmonkeypoxdynamics AT aqsaamjad fromendemictoaglobalconcernonceagainareviewofevolvingmonkeypoxdynamics AT mohammadaadilqamar fromendemictoaglobalconcernonceagainareviewofevolvingmonkeypoxdynamics AT syedfaisalmahmood fromendemictoaglobalconcernonceagainareviewofevolvingmonkeypoxdynamics |