Parkinsonian central pain is linked to the connectivity of the nucleus accumbens and the anterior insula

Parkinsonian central pain is linked to the connectivity of the nucleus accumbens and the anterior insula

Pain is a frequent and disabling non-motor symptom of Parkinson’s Disease (PD). Yet, no treatment to date can efficiently reduce this pain. This article investigates the brain functional connectivity of PD patients with central pain and the effects of levodopa and oxycodone on this connectivity.Thir...

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Main Authors: Karel Joineau, Mathilde Boussac, Patrice Peran, David Devos, Jean Luc Houeto, Sophie Drapier, David Maltete, Jesus Aguilar, Estelle Harroch, Margherita Fabbri, Clémence Leung, Fabienne Ory-Magne, Melissa Tir, Christine Tranchant, Hayet Salhi, Solène Frismand, Frederique Fluchere, Ana Marques, Olivier Rascol, Emeline Descamps, Christine Brefel-Courbon
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:NeuroImage: Reports
Subjects:
Parkinson’s disease
Pain
Resting state
Functional connectivity
Levodopa
Oxycodone
Online Access:http://www.sciencedirect.com/science/article/pii/S2666956024000035
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