Transcriptome‑wide excavation and expression pattern analysis of the NAC transcription factors in methyl jasmonate- and sodium chloride-induced Glycyrrhiza uralensis

Abstract The NAC family is among the most extensive sets of plant-exclusive transcription factors (TFs), which are crucial for various plant development and stress response processes. Although a growing number of studies have been carried out on the NAC family in different species, it has not been c...

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Main Authors: Yuan Li, Yue Shi, Zidong Zhu, Xiao Chen, Kuangwei Cao, Jiatong Li, Chunsheng Liu, Da Li
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-82151-x
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author Yuan Li
Yue Shi
Zidong Zhu
Xiao Chen
Kuangwei Cao
Jiatong Li
Chunsheng Liu
Da Li
author_facet Yuan Li
Yue Shi
Zidong Zhu
Xiao Chen
Kuangwei Cao
Jiatong Li
Chunsheng Liu
Da Li
author_sort Yuan Li
collection DOAJ
description Abstract The NAC family is among the most extensive sets of plant-exclusive transcription factors (TFs), which are crucial for various plant development and stress response processes. Although a growing number of studies have been carried out on the NAC family in different species, it has not been characterized in Glycyrrhiza uralensis. To thoroughly understand the effects of methyl jasmonate (MeJA) and sodium chloride (NaCl) inductions on NAC TFs and investigate the underlying regulatory mechanism of NAC TFs in response to MeJA and NaCl on the biosynthesis of metabolites, we used transcriptome sequencing combined with qRT‒PCR to explore differential gene expression. Comparative transcriptomic profiling by RNA sequencing (RNA-seq) revealed differentially expressed NAC TFs between MeJA/CK (Mock Control) and NaCl/CK. KEGG pathway analysis revealed that NAC TFs involved in starch and sucrose, carbohydrate, lipid, and amino acid metabolism, as well as terpenoid, polyketide, and flavonoid pathways, can regulate the MeJA- and NaCl-induced responses of G. uralensis. This research lays the groundwork for a thorough comprehension of the regulatory mechanism of NAC TFs in response to MeJA and NaCl induction and their involvement in the accumulation of secondary metabolites, which can provide a scientific basis for the cultivation of high-quality varieties of G. uralensis.
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spelling doaj-art-5a0e8e414e244ea79aaed5739b79f57c2025-08-20T02:16:40ZengNature PortfolioScientific Reports2045-23222025-02-0115111210.1038/s41598-024-82151-xTranscriptome‑wide excavation and expression pattern analysis of the NAC transcription factors in methyl jasmonate- and sodium chloride-induced Glycyrrhiza uralensisYuan Li0Yue Shi1Zidong Zhu2Xiao Chen3Kuangwei Cao4Jiatong Li5Chunsheng Liu6Da Li7School of Biology and Medicine, Beijing City UniversitySchool of Biology and Medicine, Beijing City UniversitySchool of Biology and Medicine, Beijing City UniversitySchool of Biology and Medicine, Beijing City UniversitySchool of Biology and Medicine, Beijing City UniversitySchool of Biology and Medicine, Beijing City UniversitySchool of Chinese Materia Medica, Beijing University of Chinese MedicineSchool of Biology and Medicine, Beijing City UniversityAbstract The NAC family is among the most extensive sets of plant-exclusive transcription factors (TFs), which are crucial for various plant development and stress response processes. Although a growing number of studies have been carried out on the NAC family in different species, it has not been characterized in Glycyrrhiza uralensis. To thoroughly understand the effects of methyl jasmonate (MeJA) and sodium chloride (NaCl) inductions on NAC TFs and investigate the underlying regulatory mechanism of NAC TFs in response to MeJA and NaCl on the biosynthesis of metabolites, we used transcriptome sequencing combined with qRT‒PCR to explore differential gene expression. Comparative transcriptomic profiling by RNA sequencing (RNA-seq) revealed differentially expressed NAC TFs between MeJA/CK (Mock Control) and NaCl/CK. KEGG pathway analysis revealed that NAC TFs involved in starch and sucrose, carbohydrate, lipid, and amino acid metabolism, as well as terpenoid, polyketide, and flavonoid pathways, can regulate the MeJA- and NaCl-induced responses of G. uralensis. This research lays the groundwork for a thorough comprehension of the regulatory mechanism of NAC TFs in response to MeJA and NaCl induction and their involvement in the accumulation of secondary metabolites, which can provide a scientific basis for the cultivation of high-quality varieties of G. uralensis.https://doi.org/10.1038/s41598-024-82151-xGlycyrrhiza uralensisNAC transcription factorMeJA inductionNaCl inductionTranscriptome analysis
spellingShingle Yuan Li
Yue Shi
Zidong Zhu
Xiao Chen
Kuangwei Cao
Jiatong Li
Chunsheng Liu
Da Li
Transcriptome‑wide excavation and expression pattern analysis of the NAC transcription factors in methyl jasmonate- and sodium chloride-induced Glycyrrhiza uralensis
Scientific Reports
Glycyrrhiza uralensis
NAC transcription factor
MeJA induction
NaCl induction
Transcriptome analysis
title Transcriptome‑wide excavation and expression pattern analysis of the NAC transcription factors in methyl jasmonate- and sodium chloride-induced Glycyrrhiza uralensis
title_full Transcriptome‑wide excavation and expression pattern analysis of the NAC transcription factors in methyl jasmonate- and sodium chloride-induced Glycyrrhiza uralensis
title_fullStr Transcriptome‑wide excavation and expression pattern analysis of the NAC transcription factors in methyl jasmonate- and sodium chloride-induced Glycyrrhiza uralensis
title_full_unstemmed Transcriptome‑wide excavation and expression pattern analysis of the NAC transcription factors in methyl jasmonate- and sodium chloride-induced Glycyrrhiza uralensis
title_short Transcriptome‑wide excavation and expression pattern analysis of the NAC transcription factors in methyl jasmonate- and sodium chloride-induced Glycyrrhiza uralensis
title_sort transcriptome wide excavation and expression pattern analysis of the nac transcription factors in methyl jasmonate and sodium chloride induced glycyrrhiza uralensis
topic Glycyrrhiza uralensis
NAC transcription factor
MeJA induction
NaCl induction
Transcriptome analysis
url https://doi.org/10.1038/s41598-024-82151-x
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