Evolving Immuno-Chemotherapeutic Paradigms in Esophageal and Gastric Cancers

Esophageal (EC) and gastric (GC) cancers represent severe global health issues. Within the last 18 months, the standard of care has significantly evolved for the first-line setting of advanced EC and GC within the field of human epidermal growth factor receptor 2 (HER2)-negative and HER2-positive pa...

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Main Author: Alexander Siebenhuener
Format: Article
Language:English
Published: THE HEALTHBOOK COMPANY LTD. 2021-12-01
Series:healthbook TIMES. Oncology Hematology
Online Access:https://doi.org/10.36000/hbT.OH.2021.10.054
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author Alexander Siebenhuener
author_facet Alexander Siebenhuener
author_sort Alexander Siebenhuener
collection DOAJ
description Esophageal (EC) and gastric (GC) cancers represent severe global health issues. Within the last 18 months, the standard of care has significantly evolved for the first-line setting of advanced EC and GC within the field of human epidermal growth factor receptor 2 (HER2)-negative and HER2-positive patients. The breakthrough concepts for clinical practice of immune checkpoint inhibitors (ICIs) plus chemotherapy in both fields were presented at major oncology meetings over the last 2 years. This review summarizes the latest results on when and how to use the new combinations and highlights the unsolved issues in this new era.
format Article
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institution OA Journals
issn 2673-2092
2673-2106
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publishDate 2021-12-01
publisher THE HEALTHBOOK COMPANY LTD.
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series healthbook TIMES. Oncology Hematology
spelling doaj-art-59f37092b3b940c68dc8af3dcde50d4e2025-08-20T01:56:14ZengTHE HEALTHBOOK COMPANY LTD.healthbook TIMES. Oncology Hematology2673-20922673-21062021-12-0110410.36000/hbT.OH.2021.10.054Evolving Immuno-Chemotherapeutic Paradigms in Esophageal and Gastric CancersAlexander SiebenhuenerEsophageal (EC) and gastric (GC) cancers represent severe global health issues. Within the last 18 months, the standard of care has significantly evolved for the first-line setting of advanced EC and GC within the field of human epidermal growth factor receptor 2 (HER2)-negative and HER2-positive patients. The breakthrough concepts for clinical practice of immune checkpoint inhibitors (ICIs) plus chemotherapy in both fields were presented at major oncology meetings over the last 2 years. This review summarizes the latest results on when and how to use the new combinations and highlights the unsolved issues in this new era.https://doi.org/10.36000/hbT.OH.2021.10.054
spellingShingle Alexander Siebenhuener
Evolving Immuno-Chemotherapeutic Paradigms in Esophageal and Gastric Cancers
healthbook TIMES. Oncology Hematology
title Evolving Immuno-Chemotherapeutic Paradigms in Esophageal and Gastric Cancers
title_full Evolving Immuno-Chemotherapeutic Paradigms in Esophageal and Gastric Cancers
title_fullStr Evolving Immuno-Chemotherapeutic Paradigms in Esophageal and Gastric Cancers
title_full_unstemmed Evolving Immuno-Chemotherapeutic Paradigms in Esophageal and Gastric Cancers
title_short Evolving Immuno-Chemotherapeutic Paradigms in Esophageal and Gastric Cancers
title_sort evolving immuno chemotherapeutic paradigms in esophageal and gastric cancers
url https://doi.org/10.36000/hbT.OH.2021.10.054
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