Quantifying the tumour vasculature environment from CD-31 immunohistochemistry images of breast cancer using deep learning based semantic segmentation

Quantifying the tumour vasculature environment from CD-31 immunohistochemistry images of breast cancer using deep learning based semantic segmentation

Abstract Background Tumour vascular density assessed from CD-31 immunohistochemistry (IHC) images has previously been shown to have prognostic value in breast cancer. Current methods to measure vascular density, however, are time-consuming, suffer from high inter-observer variability and are limited...

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Main Authors: Tristan Whitmarsh, Wei Cope, Julia Carmona-Bozo, Roido Manavaki, Stephen-John Sammut, Ramona Woitek, Elena Provenzano, Emma L. Brown, Sarah E. Bohndiek, Ferdia A. Gallagher, Carlos Caldas, Fiona J. Gilbert, Florian Markowetz
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Breast Cancer Research
Online Access:https://doi.org/10.1186/s13058-024-01950-2
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