Unlocking the full compositional control of hydrophilic and hydrophobic deep eutectic solvents over protein structure and stability

Abstract Deep eutectic solvents (DESs) have emerged as powerful environments to enhance enzymatic reactions, formulate therapeutic proteins, and develop protein-based biomaterials. Despite the wide range of properties that could be achievable through the compositional design of DESs, protein solubil...

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Bibliographic Details
Main Authors: Adrian Sanchez-Fernandez, Jake H. Nicholson, Susana M. Meza Huaman, Claudia Almuzara Romero, Jia-Fei Poon, Sylvain Prevost, Alex P. S. Brogan
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-025-01571-6
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