Early Recognition of Type 2 Diabetes Complications and Use of SGLT2i in Multidisciplinary Approach: Indonesian Perspective - An Expert Opinion
Indonesia ranks seventh with the highest number of cases of type 2 diabetes mellitus (T2DM). T2DM is associated with major undesirable complications including cardiovascular disease and chronic kidney disease. Kidneys play a major role in maintaining glucose homeostasis, leading the development of s...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2023-01-01
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| Series: | Acta Medica Indonesiana |
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| Online Access: | http://www.actamedindones.org/index.php/ijim/article/view/2143 |
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| author | Aida Lydia Ketut Suastika Pranawa Martosuwignjo Roy Panusunan Sibarani Sally Aman Nasution Soebagijo Adi Sulistijo |
| author_facet | Aida Lydia Ketut Suastika Pranawa Martosuwignjo Roy Panusunan Sibarani Sally Aman Nasution Soebagijo Adi Sulistijo |
| author_sort | Aida Lydia |
| collection | DOAJ |
| description | Indonesia ranks seventh with the highest number of cases of type 2 diabetes mellitus (T2DM). T2DM is associated with major undesirable complications including cardiovascular disease and chronic kidney disease. Kidneys play a major role in maintaining glucose homeostasis, leading the development of sodium glucose transporter inhibitors (SGLT2i). These inhibitors block renal sodium and glucose reabsorption. Several cardiovascular trials proved that SGLT2i have cardioprotective and renoprotective roles and have been suggested as a drug of choice in primary and secondary prevention and management of cardiorenal complications associated with T2DM. This review highlights the need for a multidisciplinary recommendation for T2DM management in Indonesian population. Additionally, it is vital to provide the perspective of Indonesian medical experts in terms of screening, diagnosis and treatment as the outcome differs geographically.
An expert panel of 6 members from Indonesia was convened to review the existing literature and develop an expert-based review/ summary on this topic. Members were chosen for their proficiency in diabetes, kidney disease and cardiovascular disease. The experts opined that the early use of SGLT2i will be effective in preventing and minimising the progression of cardiorenal complications. Moreover, a consistent multidimensional approach is necessary for improved outcomes.
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| format | Article |
| id | doaj-art-59e79cf942d5489a980afaec4769bf4c |
| institution | DOAJ |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-59e79cf942d5489a980afaec4769bf4c2025-08-20T03:17:58ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322023-01-01544Early Recognition of Type 2 Diabetes Complications and Use of SGLT2i in Multidisciplinary Approach: Indonesian Perspective - An Expert OpinionAida Lydia0Ketut Suastika1Pranawa Martosuwignjo2Roy Panusunan Sibarani3Sally Aman Nasution4Soebagijo Adi Sulistijo5Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Dr Cipto Mangunkusumo Hospital, Jakarta, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Universitas Udayana - Sanglah Hospital, Denpasar, Bali, IndonesiaIndonesian Society of Nephrology.EMC Hospital, Sentul city, Bogor, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Universitas Indonesia - Dr Cipto Mangunkusumo Hospital, Jakarta, IndonesiaDepartment of Internal Medicine, Faculty of Medicine Universitas Airlangga - Dr. Soetomo Hospital, Surabaya, Indonesia.Indonesia ranks seventh with the highest number of cases of type 2 diabetes mellitus (T2DM). T2DM is associated with major undesirable complications including cardiovascular disease and chronic kidney disease. Kidneys play a major role in maintaining glucose homeostasis, leading the development of sodium glucose transporter inhibitors (SGLT2i). These inhibitors block renal sodium and glucose reabsorption. Several cardiovascular trials proved that SGLT2i have cardioprotective and renoprotective roles and have been suggested as a drug of choice in primary and secondary prevention and management of cardiorenal complications associated with T2DM. This review highlights the need for a multidisciplinary recommendation for T2DM management in Indonesian population. Additionally, it is vital to provide the perspective of Indonesian medical experts in terms of screening, diagnosis and treatment as the outcome differs geographically. An expert panel of 6 members from Indonesia was convened to review the existing literature and develop an expert-based review/ summary on this topic. Members were chosen for their proficiency in diabetes, kidney disease and cardiovascular disease. The experts opined that the early use of SGLT2i will be effective in preventing and minimising the progression of cardiorenal complications. Moreover, a consistent multidimensional approach is necessary for improved outcomes. http://www.actamedindones.org/index.php/ijim/article/view/2143Type 2 Diabetes MellitusSGLT2iCardiorenal complications |
| spellingShingle | Aida Lydia Ketut Suastika Pranawa Martosuwignjo Roy Panusunan Sibarani Sally Aman Nasution Soebagijo Adi Sulistijo Early Recognition of Type 2 Diabetes Complications and Use of SGLT2i in Multidisciplinary Approach: Indonesian Perspective - An Expert Opinion Acta Medica Indonesiana Type 2 Diabetes Mellitus SGLT2i Cardiorenal complications |
| title | Early Recognition of Type 2 Diabetes Complications and Use of SGLT2i in Multidisciplinary Approach: Indonesian Perspective - An Expert Opinion |
| title_full | Early Recognition of Type 2 Diabetes Complications and Use of SGLT2i in Multidisciplinary Approach: Indonesian Perspective - An Expert Opinion |
| title_fullStr | Early Recognition of Type 2 Diabetes Complications and Use of SGLT2i in Multidisciplinary Approach: Indonesian Perspective - An Expert Opinion |
| title_full_unstemmed | Early Recognition of Type 2 Diabetes Complications and Use of SGLT2i in Multidisciplinary Approach: Indonesian Perspective - An Expert Opinion |
| title_short | Early Recognition of Type 2 Diabetes Complications and Use of SGLT2i in Multidisciplinary Approach: Indonesian Perspective - An Expert Opinion |
| title_sort | early recognition of type 2 diabetes complications and use of sglt2i in multidisciplinary approach indonesian perspective an expert opinion |
| topic | Type 2 Diabetes Mellitus SGLT2i Cardiorenal complications |
| url | http://www.actamedindones.org/index.php/ijim/article/view/2143 |
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