Shared diagnostic genes and potential mechanism between PCOS and recurrent implantation failure revealed by integrated transcriptomic analysis and machine learning

Shared diagnostic genes and potential mechanism between PCOS and recurrent implantation failure revealed by integrated transcriptomic analysis and machine learning

Polycystic ovary syndrome (PCOS) is a complex endocrine metabolic disorder that affects 5–10% of women of reproductive age. The endometrium of women with PCOS has altered immune cells resulting in chronic low-grade inflammation, which attribute to recurrent implantation failure (RIF). In this study,...

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Bibliographic Details
Main Authors: Wenhui Chen, Qingling Yang, Linli Hu, Mengchen Wang, Ziyao Yang, Xinxin Zeng, Yingpu Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
PCOS
RIF (Recurrent Implantation Failure)
integrated transcriptomic analysis
machine learning
TCA cycle
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1175384/full
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