The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent
Hydroxyapatite (HAp) was combined with amino-functionalized carbon quantum dots (CQDs) to enhance the optical and surface area properties of HAp. The loading of amino-functionalized CQDs could enhance the luminescence of HAp and its UV–Vis absorbance. Additionally, surface area of HAp could be incre...
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| Format: | Article |
| Language: | English |
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Académie des sciences
2022-10-01
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| Series: | Comptes Rendus. Chimie |
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| Online Access: | https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.206/ |
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| author | Hui, Khee Chung Dhanapalan, Nagaammai Khayrani, Apriliana Cahya Imanto, Teguh Sambudi, Nonni Soraya |
| author_facet | Hui, Khee Chung Dhanapalan, Nagaammai Khayrani, Apriliana Cahya Imanto, Teguh Sambudi, Nonni Soraya |
| author_sort | Hui, Khee Chung |
| collection | DOAJ |
| description | Hydroxyapatite (HAp) was combined with amino-functionalized carbon quantum dots (CQDs) to enhance the optical and surface area properties of HAp. The loading of amino-functionalized CQDs could enhance the luminescence of HAp and its UV–Vis absorbance. Additionally, surface area of HAp could be increased from 84.16 to 129.94 m$^{2}$/g by loading amino-functionalized CQDs. The drug release experiment was conducted using acetaminophen. The release happened slowly for amino-functionalized CQDs/HAp, with full release of acetaminophen being observed after 24 h. The enhanced luminescence composite shows high potential for the composite to be used for the controlled release of drugs. |
| format | Article |
| id | doaj-art-59dd49abd7f54b19a535e1684d77603b |
| institution | Kabale University |
| issn | 1878-1543 |
| language | English |
| publishDate | 2022-10-01 |
| publisher | Académie des sciences |
| record_format | Article |
| series | Comptes Rendus. Chimie |
| spelling | doaj-art-59dd49abd7f54b19a535e1684d77603b2025-02-07T13:31:13ZengAcadémie des sciencesComptes Rendus. Chimie1878-15432022-10-0125G129530610.5802/crchim.20610.5802/crchim.206The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agentHui, Khee Chung0Dhanapalan, Nagaammai1Khayrani, Apriliana Cahya2https://orcid.org/0000-0001-9160-7446Imanto, Teguh3https://orcid.org/0000-0002-6171-925XSambudi, Nonni Soraya4https://orcid.org/0000-0002-8658-1955Department of Chemical Engineering, Universiti Teknologi PETRONAS, Seri Iskandar, 32610 Perak, MalaysiaDepartment of Chemical Engineering, Universiti Teknologi PETRONAS, Seri Iskandar, 32610 Perak, MalaysiaDivision of Bioprocess Engineering, Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, 16424, West Java, IndonesiaFaculty of Pharmacy, Universitas Muhammadiyah Surakarta, Jl. A. Yani Tromol Pos 1 Pabelan, Kartasura, Sukoharjo, 57162, IndonesiaDepartment of Chemical Engineering, Universitas Pertamina, Simprug, Jakarta 12220, IndonesiaHydroxyapatite (HAp) was combined with amino-functionalized carbon quantum dots (CQDs) to enhance the optical and surface area properties of HAp. The loading of amino-functionalized CQDs could enhance the luminescence of HAp and its UV–Vis absorbance. Additionally, surface area of HAp could be increased from 84.16 to 129.94 m$^{2}$/g by loading amino-functionalized CQDs. The drug release experiment was conducted using acetaminophen. The release happened slowly for amino-functionalized CQDs/HAp, with full release of acetaminophen being observed after 24 h. The enhanced luminescence composite shows high potential for the composite to be used for the controlled release of drugs.https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.206/HydroxyapatiteDrug deliveryCarbon quantum dotsChitosanAcetaminophen |
| spellingShingle | Hui, Khee Chung Dhanapalan, Nagaammai Khayrani, Apriliana Cahya Imanto, Teguh Sambudi, Nonni Soraya The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent Comptes Rendus. Chimie Hydroxyapatite Drug delivery Carbon quantum dots Chitosan Acetaminophen |
| title | The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent |
| title_full | The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent |
| title_fullStr | The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent |
| title_full_unstemmed | The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent |
| title_short | The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent |
| title_sort | synthesis of amino functionalized carbon quantum dots decorated hydroxyapatite as drug delivery agent |
| topic | Hydroxyapatite Drug delivery Carbon quantum dots Chitosan Acetaminophen |
| url | https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.206/ |
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