Resistance to SARS-CoV-2 infection in camelid nasal organoids is associated with lack of ACE2 expression

Resistance to SARS-CoV-2 infection in camelid nasal organoids is associated with lack of ACE2 expression

Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects a variety of animal species. Susceptibility to SARS-CoV-2 is primarily determined by the utilization of the viral receptor, ACE2. SARS-CoV-2 can utilize a broad range of animal ACE2 isoforms in vitro, including the ACE...

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Bibliographic Details
Main Authors: Tim I. Breugem, Samra Riesebosch, Debby Schipper, Anna Z. Mykytyn, Petra van den Doel, Joaquim Segalés, Mart M. Lamers, Bart L. Haagmans
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Series:npj Viruses
Online Access:https://doi.org/10.1038/s44298-024-00054-0
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