Rapidly Escalating Hepcidin and Associated Serum Iron Starvation Are Features of the Acute Response to Typhoid Infection in Humans.

<h4>Background</h4>Iron is a key pathogenic determinant of many infectious diseases. Hepcidin, the hormone responsible for governing systemic iron homeostasis, is widely hypothesized to represent a key component of nutritional immunity through regulating the accessibility of iron to inva...

Full description

Saved in:
Bibliographic Details
Main Authors: Thomas C Darton, Christoph J Blohmke, Eleni Giannoulatou, Claire S Waddington, Claire Jones, Pamela Sturges, Craig Webster, Hal Drakesmith, Andrew J Pollard, Andrew E Armitage
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0004029&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!