Rapidly Escalating Hepcidin and Associated Serum Iron Starvation Are Features of the Acute Response to Typhoid Infection in Humans.
<h4>Background</h4>Iron is a key pathogenic determinant of many infectious diseases. Hepcidin, the hormone responsible for governing systemic iron homeostasis, is widely hypothesized to represent a key component of nutritional immunity through regulating the accessibility of iron to inva...
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| Main Authors: | Thomas C Darton, Christoph J Blohmke, Eleni Giannoulatou, Claire S Waddington, Claire Jones, Pamela Sturges, Craig Webster, Hal Drakesmith, Andrew J Pollard, Andrew E Armitage |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-09-01
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| Series: | PLoS Neglected Tropical Diseases |
| Online Access: | https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0004029&type=printable |
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