Korelasi Glukosa Kapiler Metode Glucose Dehidrogenase-Nicotinamide Adenine Dinucleotide Dengan Glukosa Serum Metode Heksokinase
Rapid and accurate measurement of capillary glucose level using point-of-care testing (POCT) is needed to maintain the patient’s normoglycemic status in obtaining adequate management. The glucose POCT method should be evaluated to determine analytical performance by comparing with the hexokinase met...
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Faculty of Medicine at Universitas Andalas
2022-01-01
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| Series: | Jurnal Kesehatan Andalas |
| Online Access: | http://jurnal.fk.unand.ac.id/index.php/jka/article/view/1827 |
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| author | Syarifah Tridani Fitria Rismawati Yaswir Efrida Efrida |
| author_facet | Syarifah Tridani Fitria Rismawati Yaswir Efrida Efrida |
| author_sort | Syarifah Tridani Fitria |
| collection | DOAJ |
| description | Rapid and accurate measurement of capillary glucose level using point-of-care testing (POCT) is needed to maintain the patient’s normoglycemic status in obtaining adequate management. The glucose POCT method should be evaluated to determine analytical performance by comparing with the hexokinase method as a reference method to provide accurate and reliable results. Objectives: To determined the correlation between capillary glucose using glucose dehydrogenase-nicotinamide adenine dinucleotide (GDH-NAD) and serum glucose hexokinase methods. Methods: This analytic cross-sectional study on 42 outpatients who underwent fasting blood glucose examination at Dr. M Djamil Padang General Hospital. This study was conducted from February until September 2020. Capillary fasting blood glucose was measured using glucose POCT GDH-NAD method and serum glucose with hexokinase method. The Spearman correlation test was used to analyze data, significant if p<0.05. Results: The subjects were 28 male (66.7%),14 female (33.3%) with mean age and hematocrit level was 56.12±12.97 years and 40.90±2.42%, respectively. The median capillary glucose GDH-NAD method and serum glucose hexokinase method were 100.00 mg/dL each, with a median difference was 3.00 mg/dL. Spearman correlation test showed very strong positive correlation and statistically significant (r=0,961;p=<0,001). Conclusion: Capillary glucose GDH-NAD method had a very strong positive correlation with serum glucose hexokinase method.
Keywords: hexokinase, fasting glucose level, GDH-NAD, glucose POCT |
| format | Article |
| id | doaj-art-59d81d9c2b6b4b3b9f4bd869ac2e7ca8 |
| institution | Kabale University |
| issn | 2301-7406 2615-1138 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Faculty of Medicine at Universitas Andalas |
| record_format | Article |
| series | Jurnal Kesehatan Andalas |
| spelling | doaj-art-59d81d9c2b6b4b3b9f4bd869ac2e7ca82025-02-03T03:39:17ZengFaculty of Medicine at Universitas AndalasJurnal Kesehatan Andalas2301-74062615-11382022-01-0110318318810.25077/jka.v10i3.18271201Korelasi Glukosa Kapiler Metode Glucose Dehidrogenase-Nicotinamide Adenine Dinucleotide Dengan Glukosa Serum Metode HeksokinaseSyarifah Tridani Fitria0Rismawati Yaswir1Efrida Efrida2Pogram Pendidikan Dokter Spesialis I Patologi Klinik, Faculty of Medicine, Universitas Andalas, PadangBagian Patologi Klinik dan Kedokteran Laboratorium, Faculty of Medicine, Universitas Andalas, Padang.Bagian Patologi Klinik dan Kedokteran Laboratorium, Faculty of Medicine, Universitas Andalas, Padang.Rapid and accurate measurement of capillary glucose level using point-of-care testing (POCT) is needed to maintain the patient’s normoglycemic status in obtaining adequate management. The glucose POCT method should be evaluated to determine analytical performance by comparing with the hexokinase method as a reference method to provide accurate and reliable results. Objectives: To determined the correlation between capillary glucose using glucose dehydrogenase-nicotinamide adenine dinucleotide (GDH-NAD) and serum glucose hexokinase methods. Methods: This analytic cross-sectional study on 42 outpatients who underwent fasting blood glucose examination at Dr. M Djamil Padang General Hospital. This study was conducted from February until September 2020. Capillary fasting blood glucose was measured using glucose POCT GDH-NAD method and serum glucose with hexokinase method. The Spearman correlation test was used to analyze data, significant if p<0.05. Results: The subjects were 28 male (66.7%),14 female (33.3%) with mean age and hematocrit level was 56.12±12.97 years and 40.90±2.42%, respectively. The median capillary glucose GDH-NAD method and serum glucose hexokinase method were 100.00 mg/dL each, with a median difference was 3.00 mg/dL. Spearman correlation test showed very strong positive correlation and statistically significant (r=0,961;p=<0,001). Conclusion: Capillary glucose GDH-NAD method had a very strong positive correlation with serum glucose hexokinase method. Keywords: hexokinase, fasting glucose level, GDH-NAD, glucose POCThttp://jurnal.fk.unand.ac.id/index.php/jka/article/view/1827 |
| spellingShingle | Syarifah Tridani Fitria Rismawati Yaswir Efrida Efrida Korelasi Glukosa Kapiler Metode Glucose Dehidrogenase-Nicotinamide Adenine Dinucleotide Dengan Glukosa Serum Metode Heksokinase Jurnal Kesehatan Andalas |
| title | Korelasi Glukosa Kapiler Metode Glucose Dehidrogenase-Nicotinamide Adenine Dinucleotide Dengan Glukosa Serum Metode Heksokinase |
| title_full | Korelasi Glukosa Kapiler Metode Glucose Dehidrogenase-Nicotinamide Adenine Dinucleotide Dengan Glukosa Serum Metode Heksokinase |
| title_fullStr | Korelasi Glukosa Kapiler Metode Glucose Dehidrogenase-Nicotinamide Adenine Dinucleotide Dengan Glukosa Serum Metode Heksokinase |
| title_full_unstemmed | Korelasi Glukosa Kapiler Metode Glucose Dehidrogenase-Nicotinamide Adenine Dinucleotide Dengan Glukosa Serum Metode Heksokinase |
| title_short | Korelasi Glukosa Kapiler Metode Glucose Dehidrogenase-Nicotinamide Adenine Dinucleotide Dengan Glukosa Serum Metode Heksokinase |
| title_sort | korelasi glukosa kapiler metode glucose dehidrogenase nicotinamide adenine dinucleotide dengan glukosa serum metode heksokinase |
| url | http://jurnal.fk.unand.ac.id/index.php/jka/article/view/1827 |
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