Strategies for the Endoscopic Management and Post-Resection Treatment of Superficial Esophageal Squamous Cell Carcinoma

Endoscopic resection (ER) is preferred for treating superficial esophageal squamous cell carcinoma (SESCC) that has a low risk of lymph node metastasis; the preference is due to the technique’s minimal invasiveness and having outcomes comparable to those of surgical resection, in suitable cases. Det...

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Main Author: Hyun Ho Choi
Format: Article
Language:English
Published: Korean College of Helicobacter and Upper Gastrointestinal Research 2024-03-01
Series:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Subjects:
Online Access:http://helicojournal.org/upload/pdf/kjhugr-2024-0009.pdf
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author Hyun Ho Choi
author_facet Hyun Ho Choi
author_sort Hyun Ho Choi
collection DOAJ
description Endoscopic resection (ER) is preferred for treating superficial esophageal squamous cell carcinoma (SESCC) that has a low risk of lymph node metastasis; the preference is due to the technique’s minimal invasiveness and having outcomes comparable to those of surgical resection, in suitable cases. Determining the appropriateness of ER requires a multidisciplinary review involving a pathological examination of the tumor’s depth, size, and lymphovascular invasion following resection of a specimen. According to the Korean guidelines, no additional treatment is necessary after a complete en bloc resection of SESCC that lacks submucosal invasion and lymphovascular invasion. In cases of non-curative resection for tumors that exhibit submucosal invasion, lymphovascular invasion, or positive margins, additional treatment (e.g., esophagectomy or chemoradiotherapy) is recommended. Due to the uncertainty regarding which treatment is more effective, tailored therapy that is based on patient factors and tumor characteristics is needed to maximize patient long-term survival and improve quality of life.
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issn 1738-3331
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publisher Korean College of Helicobacter and Upper Gastrointestinal Research
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series The Korean Journal of Helicobacter and Upper Gastrointestinal Research
spelling doaj-art-59d3fc6cb59c45f09dfe8320de07d9af2025-08-20T03:33:21ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312024-03-01241404410.7704/kjhugr.2024.0009820Strategies for the Endoscopic Management and Post-Resection Treatment of Superficial Esophageal Squamous Cell CarcinomaHyun Ho ChoiEndoscopic resection (ER) is preferred for treating superficial esophageal squamous cell carcinoma (SESCC) that has a low risk of lymph node metastasis; the preference is due to the technique’s minimal invasiveness and having outcomes comparable to those of surgical resection, in suitable cases. Determining the appropriateness of ER requires a multidisciplinary review involving a pathological examination of the tumor’s depth, size, and lymphovascular invasion following resection of a specimen. According to the Korean guidelines, no additional treatment is necessary after a complete en bloc resection of SESCC that lacks submucosal invasion and lymphovascular invasion. In cases of non-curative resection for tumors that exhibit submucosal invasion, lymphovascular invasion, or positive margins, additional treatment (e.g., esophagectomy or chemoradiotherapy) is recommended. Due to the uncertainty regarding which treatment is more effective, tailored therapy that is based on patient factors and tumor characteristics is needed to maximize patient long-term survival and improve quality of life.http://helicojournal.org/upload/pdf/kjhugr-2024-0009.pdfesophageal squamous cell carcinomaendoscopic mucosal resectionendoscopic submucosal dissectionlymph node metastasis
spellingShingle Hyun Ho Choi
Strategies for the Endoscopic Management and Post-Resection Treatment of Superficial Esophageal Squamous Cell Carcinoma
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
esophageal squamous cell carcinoma
endoscopic mucosal resection
endoscopic submucosal dissection
lymph node metastasis
title Strategies for the Endoscopic Management and Post-Resection Treatment of Superficial Esophageal Squamous Cell Carcinoma
title_full Strategies for the Endoscopic Management and Post-Resection Treatment of Superficial Esophageal Squamous Cell Carcinoma
title_fullStr Strategies for the Endoscopic Management and Post-Resection Treatment of Superficial Esophageal Squamous Cell Carcinoma
title_full_unstemmed Strategies for the Endoscopic Management and Post-Resection Treatment of Superficial Esophageal Squamous Cell Carcinoma
title_short Strategies for the Endoscopic Management and Post-Resection Treatment of Superficial Esophageal Squamous Cell Carcinoma
title_sort strategies for the endoscopic management and post resection treatment of superficial esophageal squamous cell carcinoma
topic esophageal squamous cell carcinoma
endoscopic mucosal resection
endoscopic submucosal dissection
lymph node metastasis
url http://helicojournal.org/upload/pdf/kjhugr-2024-0009.pdf
work_keys_str_mv AT hyunhochoi strategiesfortheendoscopicmanagementandpostresectiontreatmentofsuperficialesophagealsquamouscellcarcinoma