DENND5B Gene Expression as a Trigger for the Development of Diabetes Mellitus–Peripheral Artery Disease: Insights from a Univariate and Multivariate Mendelian Randomization Study

DENND5B Gene Expression as a Trigger for the Development of Diabetes Mellitus–Peripheral Artery Disease: Insights from a Univariate and Multivariate Mendelian Randomization Study

Background: Peripheral artery disease (PAD) is a manifestation of systemic atherosclerosis that can result in limb pain, disability, or mortality. Notably, diabetes mellitus (DM) stands out as one of the most significant risk factors for the development of PAD. Compared to individuals with PAD but n...

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Bibliographic Details
Main Authors: Qiaoqiao Li, Fuli Cao, Xueping Gao, Yuan Xu, Bo Li, Tianyang Hu
Format: Article
Language:English
Published: Ubiquity Press 2024-12-01
Series:Global Heart
Subjects:
diabetes combined peripheral artery disease
summary-data-based mendelian randomization
multivariable mendelian randomization
Online Access:https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1373
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