Lipid nanoparticles: Composition, formulation, and application

Lipid nanoparticles (LNPs) are lead non-viral vectors for delivering nucleic acids. LNPs can efficiently encapsulate nucleic acids, protect them from degradation, enhance cellular uptake and induce endosome escape, which show high transfection efficiency and low immunogenicity. In this review, we fi...

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Bibliographic Details
Main Authors: Sijia Xu, Zhenzhen Hu, Fenglin Song, Ying Xu, Xuexiang Han
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Molecular Therapy: Methods & Clinical Development
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Online Access:http://www.sciencedirect.com/science/article/pii/S2329050125000580
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