Bilateral Primary Breast Lymphoma Masquerading as Breast Carcinoma: A Rare Case Report
Primary breast lymphoma (PBL) is a rare entity, accounting for roughly 0.5% of all primary breast tumors. It commonly presents as a lump, which is frequently confirmed based on histopathological findings, as it is difficult to differentiate from other breast primaries on imaging. On histopathology,...
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| Series: | Indian Journal of Medical and Paediatric Oncology |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1791945 |
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| author | Anusheel Anchal Vasnik Pradeep Kumar Chandrakar Vivek Choudhary |
| author_facet | Anusheel Anchal Vasnik Pradeep Kumar Chandrakar Vivek Choudhary |
| author_sort | Anusheel Anchal Vasnik |
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| description | Primary breast lymphoma (PBL) is a rare entity, accounting for roughly 0.5% of all primary breast tumors. It commonly presents as a lump, which is frequently confirmed based on histopathological findings, as it is difficult to differentiate from other breast primaries on imaging. On histopathology, the most common subtype is diffuse large B-cell lymphoma (DLBCL). Prognostic factors are age, histological grade, and stage at diagnosis. We report a case of a 44-year-old female, who came to us with a painless lump in her left breast, after having a modified radical mastectomy for a similar lump in the opposite breast, under the suspicion of carcinoma breast, 25 days ago. Postoperative histopathology report from the right breast was positive for DLBCL, similar to a tru-cut biopsy from the left breast. 18-Fludeoxyglucose-positron emission tomography (PET) scan was done, which showed no avid lesions in any other organs. The patient was started on an RCHOP chemotherapy regimen. She responded very well to the treatment. After 4 years, the patient remains disease free with no evidence of any recurrence in yearly follow-up PET scans. Awareness and clinical suspicion of PBL are critical for rapid and precise diagnosis to avoid unnecessary surgery and better treatment outcomes. |
| format | Article |
| id | doaj-art-59c5d66e7bbd4af6865508ff10a489d1 |
| institution | Kabale University |
| issn | 0971-5851 0975-2129 |
| language | English |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-59c5d66e7bbd4af6865508ff10a489d12025-08-20T03:44:50ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-212910.1055/s-0044-1791945Bilateral Primary Breast Lymphoma Masquerading as Breast Carcinoma: A Rare Case ReportAnusheel Anchal Vasnik0https://orcid.org/0000-0003-3804-6904Pradeep Kumar Chandrakar1https://orcid.org/0000-0002-9644-2334Vivek Choudhary2Department of Radiation Oncology, Regional Cancer Center, Raipur, Chhattisgarh, IndiaDepartment of Radiation Oncology, Regional Cancer Center, Raipur, Chhattisgarh, IndiaDepartment of Radiation Oncology, Regional Cancer Center, Raipur, Chhattisgarh, IndiaPrimary breast lymphoma (PBL) is a rare entity, accounting for roughly 0.5% of all primary breast tumors. It commonly presents as a lump, which is frequently confirmed based on histopathological findings, as it is difficult to differentiate from other breast primaries on imaging. On histopathology, the most common subtype is diffuse large B-cell lymphoma (DLBCL). Prognostic factors are age, histological grade, and stage at diagnosis. We report a case of a 44-year-old female, who came to us with a painless lump in her left breast, after having a modified radical mastectomy for a similar lump in the opposite breast, under the suspicion of carcinoma breast, 25 days ago. Postoperative histopathology report from the right breast was positive for DLBCL, similar to a tru-cut biopsy from the left breast. 18-Fludeoxyglucose-positron emission tomography (PET) scan was done, which showed no avid lesions in any other organs. The patient was started on an RCHOP chemotherapy regimen. She responded very well to the treatment. After 4 years, the patient remains disease free with no evidence of any recurrence in yearly follow-up PET scans. Awareness and clinical suspicion of PBL are critical for rapid and precise diagnosis to avoid unnecessary surgery and better treatment outcomes.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1791945primary breast lymphomabreast carcinomaDLBCLRCHOPIHC |
| spellingShingle | Anusheel Anchal Vasnik Pradeep Kumar Chandrakar Vivek Choudhary Bilateral Primary Breast Lymphoma Masquerading as Breast Carcinoma: A Rare Case Report Indian Journal of Medical and Paediatric Oncology primary breast lymphoma breast carcinoma DLBCL RCHOP IHC |
| title | Bilateral Primary Breast Lymphoma Masquerading as Breast Carcinoma: A Rare Case Report |
| title_full | Bilateral Primary Breast Lymphoma Masquerading as Breast Carcinoma: A Rare Case Report |
| title_fullStr | Bilateral Primary Breast Lymphoma Masquerading as Breast Carcinoma: A Rare Case Report |
| title_full_unstemmed | Bilateral Primary Breast Lymphoma Masquerading as Breast Carcinoma: A Rare Case Report |
| title_short | Bilateral Primary Breast Lymphoma Masquerading as Breast Carcinoma: A Rare Case Report |
| title_sort | bilateral primary breast lymphoma masquerading as breast carcinoma a rare case report |
| topic | primary breast lymphoma breast carcinoma DLBCL RCHOP IHC |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1791945 |
| work_keys_str_mv | AT anusheelanchalvasnik bilateralprimarybreastlymphomamasqueradingasbreastcarcinomaararecasereport AT pradeepkumarchandrakar bilateralprimarybreastlymphomamasqueradingasbreastcarcinomaararecasereport AT vivekchoudhary bilateralprimarybreastlymphomamasqueradingasbreastcarcinomaararecasereport |