Understanding experiences of neglected tropical diseases of the skin: a mixed-methods study to inform intervention development in Ethiopia

Background The WHO and Ethiopia’s Ministry of Health have developed strategies to expand and integrate services for co-endemic neglected tropical diseases (NTDs) which manifest in the skin. To inform these strategies, we aimed to understand the social, economic and health system context of skin NTD...

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Main Authors: Michael Marks, David Mabey, Ruth Canter, Elizabeth Allen, Charles Opondo, Jennifer Palmer, Iris Mosweu, Jacob Novignon, Sinéad Langan, Maria Zuurmond, Catherine Pitt, Stephen L Walker, Dorothy Yeboah-Manu, Tara Mtuy, Rachel L Pullan, Richard Phillips, Daniel Okyere, Anthony Ablordey, Samantha Owen, Portia Boakye Okyere, Kidist Bobosha, Katherine Halliday, Steve Walker, Galana Mamo Ayana, Rachel Pullan, Mirgissa Kaba, Tara B Mtuy, Yaw Amoako, Adwoa Asante-Poku, Abigail Agbanyo, Eric Koka, Joseph Timothy, Yohannes Hailemichael, Abebaw Yeshambel Alemu, Teklu Cherkose, Getachew Kebebew, Fikregabrail Aberra Kassa, Tedros Nigusse, Kibur Engedawork, Zenebu Begna, Abay Waday, Saba Lambert, Katherine Elizabeth Halliday, Endalamaw Gadisa, Vanessa Yardley, Collins Ahorlu, Anita Achiaa Gyekye, Emmanuel Afreh, Esther Amon, Abraham Kwabena Anang, Ruth Dede Tuwor, Giulia D’Odorico, Kibur Engidawork, Mehari Getaneh, Bernadette Morkporkpor, Emmanuel Narh, Dorcas Opai-Tetteh, Yohannes Michael, Amel Mohammed, Fewzia Shikur Mohammed, Shimelis Doni Nigusse, Maja Niksic, Edmond Okloo, Michael Oppong, Lucy Owusu, Ishaque Siam, Ingrid Sobel, Feleke Tilahum, Joseph Tuffour, Abay Woday, Abebaw Yeshambel, Adelaide Forkuo- Boadu, Derrick Kontoh, Jojo Cobbinah
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Language:English
Published: BMJ Publishing Group 2025-02-01
Series:BMJ Global Health
Online Access:https://gh.bmj.com/content/10/2/e016650.full
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author Michael Marks
David Mabey
Ruth Canter
Elizabeth Allen
Charles Opondo
Jennifer Palmer
Iris Mosweu
Jacob Novignon
Sinéad Langan
Maria Zuurmond
Catherine Pitt
Stephen L Walker
Dorothy Yeboah-Manu
Tara Mtuy
Rachel L Pullan
Richard Phillips
Daniel Okyere
Anthony Ablordey
Samantha Owen
Portia Boakye Okyere
Kidist Bobosha
Katherine Halliday
Steve Walker
Galana Mamo Ayana
Rachel Pullan
Mirgissa Kaba
Tara B Mtuy
Yaw Amoako
Adwoa Asante-Poku
Abigail Agbanyo
Eric Koka
Joseph Timothy
Yohannes Hailemichael
Abebaw Yeshambel Alemu
Teklu Cherkose
Getachew Kebebew
Fikregabrail Aberra Kassa
Tedros Nigusse
Kibur Engedawork
Zenebu Begna
Abay Waday
Saba Lambert
Katherine Elizabeth Halliday
Endalamaw Gadisa
Vanessa Yardley
Collins Ahorlu
Anita Achiaa Gyekye
Emmanuel Afreh
Esther Amon
Abraham Kwabena Anang
Ruth Dede Tuwor
Giulia D’Odorico
Kibur Engidawork
Mehari Getaneh
Bernadette Morkporkpor
Emmanuel Narh
Dorcas Opai-Tetteh
Yohannes Michael
Amel Mohammed
Fewzia Shikur Mohammed
Shimelis Doni Nigusse
Maja Niksic
Edmond Okloo
Michael Oppong
Lucy Owusu
Ishaque Siam
Ingrid Sobel
Feleke Tilahum
Joseph Tuffour
Abay Woday
Abebaw Yeshambel
Adelaide Forkuo- Boadu
Derrick Kontoh
Jojo Cobbinah
author_facet Michael Marks
David Mabey
Ruth Canter
Elizabeth Allen
Charles Opondo
Jennifer Palmer
Iris Mosweu
Jacob Novignon
Sinéad Langan
Maria Zuurmond
Catherine Pitt
Stephen L Walker
Dorothy Yeboah-Manu
Tara Mtuy
Rachel L Pullan
Richard Phillips
Daniel Okyere
Anthony Ablordey
Samantha Owen
Portia Boakye Okyere
Kidist Bobosha
Katherine Halliday
Steve Walker
Galana Mamo Ayana
Rachel Pullan
Mirgissa Kaba
Tara B Mtuy
Yaw Amoako
Adwoa Asante-Poku
Abigail Agbanyo
Eric Koka
Joseph Timothy
Yohannes Hailemichael
Abebaw Yeshambel Alemu
Teklu Cherkose
Getachew Kebebew
Fikregabrail Aberra Kassa
Tedros Nigusse
Kibur Engedawork
Zenebu Begna
Abay Waday
Saba Lambert
Katherine Elizabeth Halliday
Endalamaw Gadisa
Vanessa Yardley
Collins Ahorlu
Anita Achiaa Gyekye
Emmanuel Afreh
Esther Amon
Abraham Kwabena Anang
Ruth Dede Tuwor
Giulia D’Odorico
Kibur Engidawork
Mehari Getaneh
Bernadette Morkporkpor
Emmanuel Narh
Dorcas Opai-Tetteh
Yohannes Michael
Amel Mohammed
Fewzia Shikur Mohammed
Shimelis Doni Nigusse
Maja Niksic
Edmond Okloo
Michael Oppong
Lucy Owusu
Ishaque Siam
Ingrid Sobel
Feleke Tilahum
Joseph Tuffour
Abay Woday
Abebaw Yeshambel
Adelaide Forkuo- Boadu
Derrick Kontoh
Jojo Cobbinah
collection DOAJ
description Background The WHO and Ethiopia’s Ministry of Health have developed strategies to expand and integrate services for co-endemic neglected tropical diseases (NTDs) which manifest in the skin. To inform these strategies, we aimed to understand the social, economic and health system context of skin NTD care in Kalu woreda, Amhara region, Ethiopia, where cutaneous leishmaniasis (CL) and leprosy are endemic.Methods Between October 2020 and May 2022, we surveyed and reviewed records of 41 primary healthcare facilities and explored common disease experiences in focus group discussions (n=40) and interviews with people affected by leprosy (n=37) and CL (n=33), health workers (n=23), kebele authorities and opinion leaders (n=33) and traditional healers (n=7). Opportunities for integrated skin NTD service provision were explored through policy document review, interviews with health officials (n=25), and stakeholder meetings.Results Availability of diagnostic supplies and health worker competence to provide skin care was very limited across primary healthcare facilities, particularly for CL. People with leprosy commonly sought care from healthcare facilities, while people with CL administered self-care or sought help from traditional healers. Travel and costs of care at specialised facilities outside the district inhibited timely care-seeking for both diseases. Transmission discourses shaped different understandings of who was affected by leprosy and CL and expectations of behaviour during and after treatment. Many policy actors felt that existing supply chain interventions, decentralised treatment approaches and community engagement initiatives for leprosy could also benefit CL, but others also warned against increasing care-seeking unless CL treatment could be provided on a scale commensurate with the large burden they perceived.Conclusion Our findings demonstrate significant gaps in the provision of care for skin NTDs within primary healthcare, very different health-seeking patterns for leprosy and CL, and a need to develop new models of care, especially for CL.
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spelling doaj-art-59c54b79dc3743a89505a33da4f6cc362025-02-08T12:00:12ZengBMJ Publishing GroupBMJ Global Health2059-79082025-02-0110210.1136/bmjgh-2024-016650Understanding experiences of neglected tropical diseases of the skin: a mixed-methods study to inform intervention development in Ethiopia 0Michael Marks1David MabeyRuth CanterElizabeth AllenCharles Opondo2Jennifer Palmer3Iris MosweuJacob NovignonSinéad LanganMaria Zuurmond4Catherine Pitt5Stephen L Walker6Dorothy Yeboah-ManuTara MtuyRachel L Pullan7Richard PhillipsDaniel OkyereAnthony AblordeySamantha OwenPortia Boakye OkyereKidist BoboshaKatherine HallidaySteve WalkerGalana Mamo Ayana8Rachel PullanMirgissa Kaba9Tara B Mtuy10Yaw AmoakoAdwoa Asante-PokuAbigail AgbanyoEric KokaJoseph TimothyYohannes Hailemichael11Abebaw Yeshambel Alemu12Teklu Cherkose13Getachew Kebebew14Fikregabrail Aberra Kassa15Tedros Nigusse16Kibur Engedawork17Zenebu Begna18Abay Waday19Saba Lambert20Katherine Elizabeth Halliday21Endalamaw Gadisa22Vanessa YardleyCollins AhorluAnita Achiaa GyekyeEmmanuel AfrehEsther AmonAbraham Kwabena AnangRuth Dede TuworGiulia D’OdoricoKibur EngidaworkMehari GetanehBernadette MorkporkporEmmanuel NarhDorcas Opai-TettehYohannes MichaelAmel MohammedFewzia Shikur MohammedShimelis Doni NigusseMaja NiksicEdmond OklooMichael OppongLucy OwusuIshaque SiamIngrid SobelFeleke TilahumJoseph TuffourAbay WodayAbebaw YeshambelAdelaide Forkuo- BoaduDerrick KontohJojo CobbinahKenya National Bureau of Statistics, Nairobi, Nairobi, KenyaDepartment of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK4 Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UKDepartment of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UKDepartment of Non-communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UKDepartment of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UKDepartment of Clinical Research, London School of Hygiene & Tropical Medicine, London, UKDepartment of Disease Control, London School of Hygiene & Tropical Medicine, London, UKArmauer Hansen Research Institute, Addis Ababa, EthiopiaSchool of Public Health, Addis Ababa University, Addis Ababa, EthiopiaDepartment of Clinical Research, London School of Hygiene & Tropical Medicine, London, UKArmauer Hansen Research Institute, Addis Ababa, EthiopiaArmauer Hansen Research Institute, Addis Ababa, EthiopiaArmauer Hansen Research Institute, Addis Ababa, EthiopiaDepartment of Sociology, Debre Markos University, Debre Markos, Amhara, EthiopiaArmauer Hansen Research Institute, Addis Ababa, EthiopiaArmauer Hansen Research Institute, Addis Ababa, EthiopiaDepartment of Sociology, Addis Ababa University, Addis Ababa, EthiopiaDepartment of Public Health, Ambo University, Ambo, EthiopiaSchool of Population Health, Curtin University, Perth, Western Australia, AustraliaArmauer Hansen Research Institute, Addis Ababa, EthiopiaDepartment of Disease Control, London School of Hygiene & Tropical Medicine, London, UKArmauer Hansen Research Institute, Addis Ababa, EthiopiaBackground The WHO and Ethiopia’s Ministry of Health have developed strategies to expand and integrate services for co-endemic neglected tropical diseases (NTDs) which manifest in the skin. To inform these strategies, we aimed to understand the social, economic and health system context of skin NTD care in Kalu woreda, Amhara region, Ethiopia, where cutaneous leishmaniasis (CL) and leprosy are endemic.Methods Between October 2020 and May 2022, we surveyed and reviewed records of 41 primary healthcare facilities and explored common disease experiences in focus group discussions (n=40) and interviews with people affected by leprosy (n=37) and CL (n=33), health workers (n=23), kebele authorities and opinion leaders (n=33) and traditional healers (n=7). Opportunities for integrated skin NTD service provision were explored through policy document review, interviews with health officials (n=25), and stakeholder meetings.Results Availability of diagnostic supplies and health worker competence to provide skin care was very limited across primary healthcare facilities, particularly for CL. People with leprosy commonly sought care from healthcare facilities, while people with CL administered self-care or sought help from traditional healers. Travel and costs of care at specialised facilities outside the district inhibited timely care-seeking for both diseases. Transmission discourses shaped different understandings of who was affected by leprosy and CL and expectations of behaviour during and after treatment. Many policy actors felt that existing supply chain interventions, decentralised treatment approaches and community engagement initiatives for leprosy could also benefit CL, but others also warned against increasing care-seeking unless CL treatment could be provided on a scale commensurate with the large burden they perceived.Conclusion Our findings demonstrate significant gaps in the provision of care for skin NTDs within primary healthcare, very different health-seeking patterns for leprosy and CL, and a need to develop new models of care, especially for CL.https://gh.bmj.com/content/10/2/e016650.full
spellingShingle Michael Marks
David Mabey
Ruth Canter
Elizabeth Allen
Charles Opondo
Jennifer Palmer
Iris Mosweu
Jacob Novignon
Sinéad Langan
Maria Zuurmond
Catherine Pitt
Stephen L Walker
Dorothy Yeboah-Manu
Tara Mtuy
Rachel L Pullan
Richard Phillips
Daniel Okyere
Anthony Ablordey
Samantha Owen
Portia Boakye Okyere
Kidist Bobosha
Katherine Halliday
Steve Walker
Galana Mamo Ayana
Rachel Pullan
Mirgissa Kaba
Tara B Mtuy
Yaw Amoako
Adwoa Asante-Poku
Abigail Agbanyo
Eric Koka
Joseph Timothy
Yohannes Hailemichael
Abebaw Yeshambel Alemu
Teklu Cherkose
Getachew Kebebew
Fikregabrail Aberra Kassa
Tedros Nigusse
Kibur Engedawork
Zenebu Begna
Abay Waday
Saba Lambert
Katherine Elizabeth Halliday
Endalamaw Gadisa
Vanessa Yardley
Collins Ahorlu
Anita Achiaa Gyekye
Emmanuel Afreh
Esther Amon
Abraham Kwabena Anang
Ruth Dede Tuwor
Giulia D’Odorico
Kibur Engidawork
Mehari Getaneh
Bernadette Morkporkpor
Emmanuel Narh
Dorcas Opai-Tetteh
Yohannes Michael
Amel Mohammed
Fewzia Shikur Mohammed
Shimelis Doni Nigusse
Maja Niksic
Edmond Okloo
Michael Oppong
Lucy Owusu
Ishaque Siam
Ingrid Sobel
Feleke Tilahum
Joseph Tuffour
Abay Woday
Abebaw Yeshambel
Adelaide Forkuo- Boadu
Derrick Kontoh
Jojo Cobbinah
Understanding experiences of neglected tropical diseases of the skin: a mixed-methods study to inform intervention development in Ethiopia
BMJ Global Health
title Understanding experiences of neglected tropical diseases of the skin: a mixed-methods study to inform intervention development in Ethiopia
title_full Understanding experiences of neglected tropical diseases of the skin: a mixed-methods study to inform intervention development in Ethiopia
title_fullStr Understanding experiences of neglected tropical diseases of the skin: a mixed-methods study to inform intervention development in Ethiopia
title_full_unstemmed Understanding experiences of neglected tropical diseases of the skin: a mixed-methods study to inform intervention development in Ethiopia
title_short Understanding experiences of neglected tropical diseases of the skin: a mixed-methods study to inform intervention development in Ethiopia
title_sort understanding experiences of neglected tropical diseases of the skin a mixed methods study to inform intervention development in ethiopia
url https://gh.bmj.com/content/10/2/e016650.full
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