A case of successful intensive care of severe sepsis in a newborn child
Neonatal sepsis remains one of the key problems of perinatal medicine. Aim of the study. To acquaint practitioners with the case of successful complex intensive care in a newborn child with severe sepsis using discrete plasmapheresis. Materials and methods. The child was treated in the Departm...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Zaporizhzhia State Medical and Pharmaceutical University
2025-06-01
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| Series: | Сучасні медичні технології |
| Subjects: | |
| Online Access: | https://medtech.mphu.edu.ua/article/view/323125/322420 |
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| Summary: | Neonatal sepsis remains one of the key problems of perinatal medicine.
Aim of the study. To acquaint practitioners with the case of successful complex intensive care in a newborn child with severe sepsis using discrete plasmapheresis.
Materials and methods. The child was treated in the Department of Anaesthesiology and Intensive Care of Newborns of Zaporizhzhia City Children’s Hospital No. 5. The child underwent clinical and biochemical blood tests, microbiological, X-ray and ultrasound examinations using the hospital’s equipment.
Results. In a premature baby, the postoperative period after hernia repair was complicated by the development of necrotising enterocolitis. The child’s condition was close to critical due to the progression of toxemia, water and electrolyte disorders, acid-base imbalance, development of peritonitis, and multiple organ failure syndrome. For the purpose of extracorporeal detoxification, a discrete plasmapheresis session was performed. In order to sanitise the inflammation focus, the child’s abdominal cavity was drained from the left and right sides for washing with antiseptic solutions. After that, the child’s condition was stabilised, and an extended surgery with balanced multimodal anesthesia and neuroaxial block was performed. In post-operative period caudal blocks were performed twice daily. A second session of discrete plasmapheresis was conducted. Subsequently, immunosupplementation therapy, full parenteral nutrition, and combined antibacterial therapy according to the de-escalation principle were performed. The child’s condition was positive due to the complete regression of intoxication, intestinal paresis, and multiple organ failure. The result of complex intensive care using extracorporeal detoxification methods was positive.
Conclusions. The integration of extracorporeal detoxification methods into the comprehensive intensive treatment of severe sepsis in a newborn, in combination with de-escalation antibiotic therapy and immune replacement therapy, is likely to improve treatment outcomes. |
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| ISSN: | 2072-9367 |