Effectiveness of interventions for dry eye: a protocol for an overview of systematic reviews
Introduction Dry eye is a leading cause of ocular morbidity and economic and societal burden for patients and healthcare systems. There are several treatment options available for dry eye and high-quality systematic reviews synthesise the evidence for their effectiveness and potential harms.Methods...
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| Format: | Article |
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BMJ Publishing Group
2022-06-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/6/e058708.full |
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| author | Tianjing Li Paul McCann Riaz Qureshi Zanna Kruoch |
| author_facet | Tianjing Li Paul McCann Riaz Qureshi Zanna Kruoch |
| author_sort | Tianjing Li |
| collection | DOAJ |
| description | Introduction Dry eye is a leading cause of ocular morbidity and economic and societal burden for patients and healthcare systems. There are several treatment options available for dry eye and high-quality systematic reviews synthesise the evidence for their effectiveness and potential harms.Methods and analysis We will search the Cochrane Eyes and Vision US satellite (CEV@US) database of eyes and vision systematic reviews for systematic reviews on interventions for dry eye. CEV@US conducted an initial search of PubMed and Embase to populate the CEV@US database of eyes and vision systematic reviews in 2007, which was updated most recently in August 2021. We will search the database for systematic reviews published since 1 January 2016 because systematic reviews more than 5 years are unlikely to be up to date. We will consider Cochrane and non-Cochrane systematic reviews eligible for inclusion. Two authors will independently screen articles. We will include studies that evaluate interventions for dry eye and/or meibomian gland dysfunction with no restriction on types of participants or review language. We will select reliable systematic reviews (ie, those meeting pre-established methodological criteria) for inclusion, assessed by one investigator and verified by a second investigator. We will extract ratings of the certainty of evidence from within each review. We will report the degree of overlap for systematic reviews that answer similar questions and include overlapping primary studies. We will present results of the overview in alignment with guidelines in the Cochrane Handbook of Systematic Reviews of Interventions (Online Chapter 5: Overviews of Reviews), the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, and an overview of reviews quality and transparency checklist. The anticipated start and completion dates for this overview are 1 May 2021 and 30 April 2022, respectively.Ethics and dissemination This overview will not require the approval of an Ethics Committee because it will use published studies. We will publish results in a peer-reviewed journal.PROSPERO registration number CRD42021279880. |
| format | Article |
| id | doaj-art-59bfaa50179648019053cb802940d87e |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-59bfaa50179648019053cb802940d87e2025-01-28T01:20:11ZengBMJ Publishing GroupBMJ Open2044-60552022-06-0112610.1136/bmjopen-2021-058708Effectiveness of interventions for dry eye: a protocol for an overview of systematic reviewsTianjing Li0Paul McCann1Riaz Qureshi2Zanna Kruoch3professorDepartment of Ophthalmology, University of Colorado - Anschutz Medical Campus, Aurora, Colorado, USADepartment of Ophthalmology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USACedar Springs Eye Clinic, College of Optometry, University of Houston, Houston, Texas, USAIntroduction Dry eye is a leading cause of ocular morbidity and economic and societal burden for patients and healthcare systems. There are several treatment options available for dry eye and high-quality systematic reviews synthesise the evidence for their effectiveness and potential harms.Methods and analysis We will search the Cochrane Eyes and Vision US satellite (CEV@US) database of eyes and vision systematic reviews for systematic reviews on interventions for dry eye. CEV@US conducted an initial search of PubMed and Embase to populate the CEV@US database of eyes and vision systematic reviews in 2007, which was updated most recently in August 2021. We will search the database for systematic reviews published since 1 January 2016 because systematic reviews more than 5 years are unlikely to be up to date. We will consider Cochrane and non-Cochrane systematic reviews eligible for inclusion. Two authors will independently screen articles. We will include studies that evaluate interventions for dry eye and/or meibomian gland dysfunction with no restriction on types of participants or review language. We will select reliable systematic reviews (ie, those meeting pre-established methodological criteria) for inclusion, assessed by one investigator and verified by a second investigator. We will extract ratings of the certainty of evidence from within each review. We will report the degree of overlap for systematic reviews that answer similar questions and include overlapping primary studies. We will present results of the overview in alignment with guidelines in the Cochrane Handbook of Systematic Reviews of Interventions (Online Chapter 5: Overviews of Reviews), the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement, and an overview of reviews quality and transparency checklist. The anticipated start and completion dates for this overview are 1 May 2021 and 30 April 2022, respectively.Ethics and dissemination This overview will not require the approval of an Ethics Committee because it will use published studies. We will publish results in a peer-reviewed journal.PROSPERO registration number CRD42021279880.https://bmjopen.bmj.com/content/12/6/e058708.full |
| spellingShingle | Tianjing Li Paul McCann Riaz Qureshi Zanna Kruoch Effectiveness of interventions for dry eye: a protocol for an overview of systematic reviews BMJ Open |
| title | Effectiveness of interventions for dry eye: a protocol for an overview of systematic reviews |
| title_full | Effectiveness of interventions for dry eye: a protocol for an overview of systematic reviews |
| title_fullStr | Effectiveness of interventions for dry eye: a protocol for an overview of systematic reviews |
| title_full_unstemmed | Effectiveness of interventions for dry eye: a protocol for an overview of systematic reviews |
| title_short | Effectiveness of interventions for dry eye: a protocol for an overview of systematic reviews |
| title_sort | effectiveness of interventions for dry eye a protocol for an overview of systematic reviews |
| url | https://bmjopen.bmj.com/content/12/6/e058708.full |
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