ANTIBACTERIAL, ANTIOXIDANT, AND PHYTOCHEMICAL PROPERTIES OF BRYOPHYLLUM PINNATUM (LAM.) LEAF EXTRACTS AGAINST PATHOGENIC BACTERIA
Background: Bryophyllum pinnatum (Lam.) (Family: Crassulaceae), also known as Kalanchoe pinnatum, is a perennial herb, 3 to 5 meters tall, with opposed glabrous leaves. It is used to treat various illnesses due to its many health benefits. Purpose: This study aims to investigate the biological impor...
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Universitas Airlangga
2025-07-01
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| Series: | Journal of Vocational Health Studies |
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| Online Access: | https://e-journal.unair.ac.id/JVHS/article/view/58545 |
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| author | Elizabeth Tomilayo Akinterinwa Babayemi Olawale Oladejo Muftau Kolawole Oladunmoye |
| author_facet | Elizabeth Tomilayo Akinterinwa Babayemi Olawale Oladejo Muftau Kolawole Oladunmoye |
| author_sort | Elizabeth Tomilayo Akinterinwa |
| collection | DOAJ |
| description | Background: Bryophyllum pinnatum (Lam.) (Family: Crassulaceae), also known as Kalanchoe pinnatum, is a perennial herb, 3 to 5 meters tall, with opposed glabrous leaves. It is used to treat various illnesses due to its many health benefits. Purpose: This study aims to investigate the biological importance of B. pinnatum leaf extracts against some pathogenic bacteria. Method: Freshly harvested leaves of B. pinnatum were collected, air-dried, pulverized to powder and stored in air-tight containers using standard methods. Extracts were obtained from the powder using ethanol, ethyl acetate and distilled water. Pathogenic bacterial isolates were collected and their identity were confirmed using colonial and biochemical tests. The extracts were screened for antibacterial, antioxidant and phytochemical potentials using standard methods. Result: The highest percentage yield was obtained with the ethanol extract (12.2%) of B. pinnatum and the lowest yield (5.3 %) was obtained with the ethyl acetate extract. The ethanol extract was effective against eight (8) out of the thirteen test isolates, while the aqueous extract had the lowest activity and was effective against only two bacteria (Pseudomonas aeruginosa and Haemophillus influenzae). The lowest MIC observed with the three extracts is 25 mg/ml. B. pinnatum leaf extracts possess high antioxidant properties that are concentration dependent. The phytochemical constituents that were recorded in this study include saponins, terpenoids, steroids, tannins and glycosides. Steroid was present in only the ethanol extract but absent in the other two. Conclusion: B. pinnatum leaves have antibacterial, antioxidant and phytochemical properties and could be further utilized to manage bacterial infections. |
| format | Article |
| id | doaj-art-59ba4ea7a2a24f748b0d3db53be94477 |
| institution | DOAJ |
| issn | 2580-7161 2580-717X |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Journal of Vocational Health Studies |
| spelling | doaj-art-59ba4ea7a2a24f748b0d3db53be944772025-08-20T03:15:36ZengUniversitas AirlanggaJournal of Vocational Health Studies2580-71612580-717X2025-07-0191546310.20473/jvhs.V9.I1.2025.54-6356711ANTIBACTERIAL, ANTIOXIDANT, AND PHYTOCHEMICAL PROPERTIES OF BRYOPHYLLUM PINNATUM (LAM.) LEAF EXTRACTS AGAINST PATHOGENIC BACTERIAElizabeth Tomilayo Akinterinwa0https://orcid.org/0000-0003-4356-1708Babayemi Olawale Oladejo1https://orcid.org/0000-0002-3284-8781Muftau Kolawole Oladunmoye2https://orcid.org/0009-0008-3219-6614Microbiology Program, College of Natural and Applied Sciences, Wesley University Ondo, Ondo StateDepartment of Microbiology, School of Life Sciences, Federal University of Technology Akure, Ondo StateDepartment of Microbiology, School of Life Sciences, Federal University of Technology Akure, Ondo StateBackground: Bryophyllum pinnatum (Lam.) (Family: Crassulaceae), also known as Kalanchoe pinnatum, is a perennial herb, 3 to 5 meters tall, with opposed glabrous leaves. It is used to treat various illnesses due to its many health benefits. Purpose: This study aims to investigate the biological importance of B. pinnatum leaf extracts against some pathogenic bacteria. Method: Freshly harvested leaves of B. pinnatum were collected, air-dried, pulverized to powder and stored in air-tight containers using standard methods. Extracts were obtained from the powder using ethanol, ethyl acetate and distilled water. Pathogenic bacterial isolates were collected and their identity were confirmed using colonial and biochemical tests. The extracts were screened for antibacterial, antioxidant and phytochemical potentials using standard methods. Result: The highest percentage yield was obtained with the ethanol extract (12.2%) of B. pinnatum and the lowest yield (5.3 %) was obtained with the ethyl acetate extract. The ethanol extract was effective against eight (8) out of the thirteen test isolates, while the aqueous extract had the lowest activity and was effective against only two bacteria (Pseudomonas aeruginosa and Haemophillus influenzae). The lowest MIC observed with the three extracts is 25 mg/ml. B. pinnatum leaf extracts possess high antioxidant properties that are concentration dependent. The phytochemical constituents that were recorded in this study include saponins, terpenoids, steroids, tannins and glycosides. Steroid was present in only the ethanol extract but absent in the other two. Conclusion: B. pinnatum leaves have antibacterial, antioxidant and phytochemical properties and could be further utilized to manage bacterial infections.https://e-journal.unair.ac.id/JVHS/article/view/58545antibacterial antioxidant bacterial infections pathogenic phytochemical constituents |
| spellingShingle | Elizabeth Tomilayo Akinterinwa Babayemi Olawale Oladejo Muftau Kolawole Oladunmoye ANTIBACTERIAL, ANTIOXIDANT, AND PHYTOCHEMICAL PROPERTIES OF BRYOPHYLLUM PINNATUM (LAM.) LEAF EXTRACTS AGAINST PATHOGENIC BACTERIA Journal of Vocational Health Studies antibacterial antioxidant bacterial infections pathogenic phytochemical constituents |
| title | ANTIBACTERIAL, ANTIOXIDANT, AND PHYTOCHEMICAL PROPERTIES OF BRYOPHYLLUM PINNATUM (LAM.) LEAF EXTRACTS AGAINST PATHOGENIC BACTERIA |
| title_full | ANTIBACTERIAL, ANTIOXIDANT, AND PHYTOCHEMICAL PROPERTIES OF BRYOPHYLLUM PINNATUM (LAM.) LEAF EXTRACTS AGAINST PATHOGENIC BACTERIA |
| title_fullStr | ANTIBACTERIAL, ANTIOXIDANT, AND PHYTOCHEMICAL PROPERTIES OF BRYOPHYLLUM PINNATUM (LAM.) LEAF EXTRACTS AGAINST PATHOGENIC BACTERIA |
| title_full_unstemmed | ANTIBACTERIAL, ANTIOXIDANT, AND PHYTOCHEMICAL PROPERTIES OF BRYOPHYLLUM PINNATUM (LAM.) LEAF EXTRACTS AGAINST PATHOGENIC BACTERIA |
| title_short | ANTIBACTERIAL, ANTIOXIDANT, AND PHYTOCHEMICAL PROPERTIES OF BRYOPHYLLUM PINNATUM (LAM.) LEAF EXTRACTS AGAINST PATHOGENIC BACTERIA |
| title_sort | antibacterial antioxidant and phytochemical properties of bryophyllum pinnatum lam leaf extracts against pathogenic bacteria |
| topic | antibacterial antioxidant bacterial infections pathogenic phytochemical constituents |
| url | https://e-journal.unair.ac.id/JVHS/article/view/58545 |
| work_keys_str_mv | AT elizabethtomilayoakinterinwa antibacterialantioxidantandphytochemicalpropertiesofbryophyllumpinnatumlamleafextractsagainstpathogenicbacteria AT babayemiolawaleoladejo antibacterialantioxidantandphytochemicalpropertiesofbryophyllumpinnatumlamleafextractsagainstpathogenicbacteria AT muftaukolawoleoladunmoye antibacterialantioxidantandphytochemicalpropertiesofbryophyllumpinnatumlamleafextractsagainstpathogenicbacteria |