Immediate postoperative effects of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy using carboplatin on peritoneal tissue inflammatory and ischemic responses: an explorative porcine study

This explorative porcine study investigated the immediate postoperative response of inflammatory protein markers and ischemic metabolites in peritoneal abdominal wall tissue during and after hyperthermic intraperitoneal chemotherapy (HIPEC) assessed by microdialysis.

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Main Authors: Petersen Elisabeth Krogsgaard, Bue Mats, Harlev Christina, Jørgensen Andrea René, Hanberg Pelle, Petersen Lone Kjeld, Stilling Maiken
Format: Article
Language:English
Published: De Gruyter 2025-04-01
Series:Pleura and Peritoneum
Subjects:
Online Access:https://doi.org/10.1515/pp-2025-0001
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author Petersen Elisabeth Krogsgaard
Bue Mats
Harlev Christina
Jørgensen Andrea René
Hanberg Pelle
Petersen Lone Kjeld
Stilling Maiken
author_facet Petersen Elisabeth Krogsgaard
Bue Mats
Harlev Christina
Jørgensen Andrea René
Hanberg Pelle
Petersen Lone Kjeld
Stilling Maiken
author_sort Petersen Elisabeth Krogsgaard
collection DOAJ
description This explorative porcine study investigated the immediate postoperative response of inflammatory protein markers and ischemic metabolites in peritoneal abdominal wall tissue during and after hyperthermic intraperitoneal chemotherapy (HIPEC) assessed by microdialysis.
format Article
id doaj-art-59adb33f68534da19fc31139e16409fc
institution Kabale University
issn 2364-768X
language English
publishDate 2025-04-01
publisher De Gruyter
record_format Article
series Pleura and Peritoneum
spelling doaj-art-59adb33f68534da19fc31139e16409fc2025-08-20T03:50:11ZengDe GruyterPleura and Peritoneum2364-768X2025-04-01102698010.1515/pp-2025-0001Immediate postoperative effects of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy using carboplatin on peritoneal tissue inflammatory and ischemic responses: an explorative porcine studyPetersen Elisabeth Krogsgaard0Bue Mats1Harlev Christina2Jørgensen Andrea René3Hanberg Pelle4Petersen Lone Kjeld5Stilling Maiken6Department of Clinical Medicine, 1006Aarhus University, Aarhus, DenmarkDepartment of Clinical Medicine, 1006Aarhus University, Aarhus, DenmarkDepartment of Clinical Medicine, 1006Aarhus University, Aarhus, DenmarkDepartment of Clinical Medicine, 1006Aarhus University, Aarhus, DenmarkDepartment of Clinical Medicine, 1006Aarhus University, Aarhus, DenmarkDepartment of Gynecology and Obstetrics, Odense University Hospital, Odense, DenmarkDepartment of Clinical Medicine, 1006Aarhus University, Aarhus, DenmarkThis explorative porcine study investigated the immediate postoperative response of inflammatory protein markers and ischemic metabolites in peritoneal abdominal wall tissue during and after hyperthermic intraperitoneal chemotherapy (HIPEC) assessed by microdialysis.https://doi.org/10.1515/pp-2025-0001cytoreductive surgeryhyperthermic intraperitoneal chemotherapy (hipec)carboplatinlactateischemic metabolitesacute inflammatory protein markers
spellingShingle Petersen Elisabeth Krogsgaard
Bue Mats
Harlev Christina
Jørgensen Andrea René
Hanberg Pelle
Petersen Lone Kjeld
Stilling Maiken
Immediate postoperative effects of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy using carboplatin on peritoneal tissue inflammatory and ischemic responses: an explorative porcine study
Pleura and Peritoneum
cytoreductive surgery
hyperthermic intraperitoneal chemotherapy (hipec)
carboplatin
lactate
ischemic metabolites
acute inflammatory protein markers
title Immediate postoperative effects of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy using carboplatin on peritoneal tissue inflammatory and ischemic responses: an explorative porcine study
title_full Immediate postoperative effects of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy using carboplatin on peritoneal tissue inflammatory and ischemic responses: an explorative porcine study
title_fullStr Immediate postoperative effects of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy using carboplatin on peritoneal tissue inflammatory and ischemic responses: an explorative porcine study
title_full_unstemmed Immediate postoperative effects of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy using carboplatin on peritoneal tissue inflammatory and ischemic responses: an explorative porcine study
title_short Immediate postoperative effects of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy using carboplatin on peritoneal tissue inflammatory and ischemic responses: an explorative porcine study
title_sort immediate postoperative effects of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy using carboplatin on peritoneal tissue inflammatory and ischemic responses an explorative porcine study
topic cytoreductive surgery
hyperthermic intraperitoneal chemotherapy (hipec)
carboplatin
lactate
ischemic metabolites
acute inflammatory protein markers
url https://doi.org/10.1515/pp-2025-0001
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