Integrative multi-omics analysis and machine learning reveal the unique role of ASCC3 in combination with various immune-related genes in rectal adenocarcinoma

Integrative multi-omics analysis and machine learning reveal the unique role of ASCC3 in combination with various immune-related genes in rectal adenocarcinoma

BackgroundThe Activating Signal Cointegrator 1 (ASC-1) complex is a tetrameric complex composed of Thyroid Hormone Receptor Interactor 4 (TRIP4), Activating Signal Cointegrator 1 (ASCC1), Activating Signal Cointegrator 2 (ASCC2), and Activating Signal Cointegrator 3 (ASCC3). As the core subunit of t...

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Bibliographic Details
Main Authors: Chuang Miao, Fei Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Genetics
Subjects:
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ASCC3
machine learning
prognosis
tumor immunity
DNA damage repair
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1614946/full
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