RNF144A-VRK2-G3BP1 axis regulates stress granule assembly

RNF144A-VRK2-G3BP1 axis regulates stress granule assembly

Abstract Under the cellular stress, stress granules (SGs) help survival and proliferation of the cell. Unfortunately, the same SGs help unwanted cancer cells under stressful environment, including anti-cancer chemotherapy treatment. While SGs elevate the cancer cell’s resistance to chemotherapy, the...

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Bibliographic Details
Main Authors: Sung Wook Kim, Jae Lee, Kyung Won Jo, Young-Hun Jeong, Won Sik Shin, Kyong-Tai Kim
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02460-6
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