An Unusual Case of Recurrent Guillain-Barre Syndrome of a Different Subtype Five Years after Initial Diagnosis
We present a case of a previously healthy 17-year-old girl with history of Guillain-Barre Syndrome 5 years after initial presentation who presented with bilateral lower extremity pain, worsening dysphagia, subsequent weakness, and decreased reflexes. Cerebrospinal fluid analysis had a prominent lymp...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/356157 |
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| author | M. Dy R. L. Leshner J. R. Crawford |
| author_facet | M. Dy R. L. Leshner J. R. Crawford |
| author_sort | M. Dy |
| collection | DOAJ |
| description | We present a case of a previously healthy 17-year-old girl with history of Guillain-Barre Syndrome 5 years after initial presentation who presented with bilateral lower extremity pain, worsening dysphagia, subsequent weakness, and decreased reflexes. Cerebrospinal fluid analysis had a prominent lymphocytic pleocytosis. MRI of spine showed significant anterior nerve root enhancement. Electromyogram demonstrated a mild axonal greater than demyelinating motor polyneuropathy and intact sensory responses, with no evidence of conduction block or temporal dispersion, unlike her first presentation that revealed a demyelinating polyneuropathy. The patient recovered with mild subjective weakness following 5 days of intravenous immunoglobulin treatment. This case represents a recurrence of a predominantly motor variant polyradiculoneuropathy distinct from the initial presentation with a lymphocytic predominant CSF pleocytosis, nerve root enhancement on MRI spine, and rapid recovery following treatment with intravenous immunoglobulin. |
| format | Article |
| id | doaj-art-597f36353e2a450a9efa8b57fb45aebf |
| institution | OA Journals |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-597f36353e2a450a9efa8b57fb45aebf2025-08-20T02:05:35ZengWileyCase Reports in Neurological Medicine2090-66682090-66762013-01-01201310.1155/2013/356157356157An Unusual Case of Recurrent Guillain-Barre Syndrome of a Different Subtype Five Years after Initial DiagnosisM. Dy0R. L. Leshner1J. R. Crawford2Department of Pediatrics, University of California, San Diego and Rady Children’s Hospital, USADepartment of Pediatrics, University of California, San Diego and Rady Children’s Hospital, USADepartments of Neurosciences and Pediatrics, University of California, San Diego, Division of Child Neurology, Rady Children’s Hospital of San Diego, 8010 Frost Street, Suite 400, San Diego, CA 92123, USAWe present a case of a previously healthy 17-year-old girl with history of Guillain-Barre Syndrome 5 years after initial presentation who presented with bilateral lower extremity pain, worsening dysphagia, subsequent weakness, and decreased reflexes. Cerebrospinal fluid analysis had a prominent lymphocytic pleocytosis. MRI of spine showed significant anterior nerve root enhancement. Electromyogram demonstrated a mild axonal greater than demyelinating motor polyneuropathy and intact sensory responses, with no evidence of conduction block or temporal dispersion, unlike her first presentation that revealed a demyelinating polyneuropathy. The patient recovered with mild subjective weakness following 5 days of intravenous immunoglobulin treatment. This case represents a recurrence of a predominantly motor variant polyradiculoneuropathy distinct from the initial presentation with a lymphocytic predominant CSF pleocytosis, nerve root enhancement on MRI spine, and rapid recovery following treatment with intravenous immunoglobulin.http://dx.doi.org/10.1155/2013/356157 |
| spellingShingle | M. Dy R. L. Leshner J. R. Crawford An Unusual Case of Recurrent Guillain-Barre Syndrome of a Different Subtype Five Years after Initial Diagnosis Case Reports in Neurological Medicine |
| title | An Unusual Case of Recurrent Guillain-Barre Syndrome of a Different Subtype Five Years after Initial Diagnosis |
| title_full | An Unusual Case of Recurrent Guillain-Barre Syndrome of a Different Subtype Five Years after Initial Diagnosis |
| title_fullStr | An Unusual Case of Recurrent Guillain-Barre Syndrome of a Different Subtype Five Years after Initial Diagnosis |
| title_full_unstemmed | An Unusual Case of Recurrent Guillain-Barre Syndrome of a Different Subtype Five Years after Initial Diagnosis |
| title_short | An Unusual Case of Recurrent Guillain-Barre Syndrome of a Different Subtype Five Years after Initial Diagnosis |
| title_sort | unusual case of recurrent guillain barre syndrome of a different subtype five years after initial diagnosis |
| url | http://dx.doi.org/10.1155/2013/356157 |
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