Grey-Blue Regression in Melanoma In Situ—Evaluation on 111 Cases

As fibrosis and melanosis are often seen in malignant melanoma, the presence of dermoscopic signs of regression may represent a clue for the diagnosis of malignancy. Our aim was to assess the frequency and extent of 11 dermoscopic features of regression evaluating dermoscopic images of 111 melanomas...

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Main Authors: S. Bassoli, S. Borsari, C. Ferrari, F. Giusti, G. Pellacani, G. Ponti, S. Seidenari
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Skin Cancer
Online Access:http://dx.doi.org/10.1155/2011/180980
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author S. Bassoli
S. Borsari
C. Ferrari
F. Giusti
G. Pellacani
G. Ponti
S. Seidenari
author_facet S. Bassoli
S. Borsari
C. Ferrari
F. Giusti
G. Pellacani
G. Ponti
S. Seidenari
author_sort S. Bassoli
collection DOAJ
description As fibrosis and melanosis are often seen in malignant melanoma, the presence of dermoscopic signs of regression may represent a clue for the diagnosis of malignancy. Our aim was to assess the frequency and extent of 11 dermoscopic features of regression evaluating dermoscopic images of 111 melanomas in situ (MIS). Regression structures (grey-blue areas, white areas, peppering, and/or blue-whitish veil) were present in 80.1% of the lesions. Approximately 80% of the lesions showed regression of dermoscopic structures and light brown areas. Most lesions showed the presence of grey-blue areas (74.7%), whereas peppering was observable in 30.6% of MIS. Areas of fibrosis were mainly observable as structureless areas with a pinkish hue (50.4%). Based on our data, the reticular pattern of blue regression and light brown areas can be considered a significant discriminator and a reliable predictor of MIS.
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series Journal of Skin Cancer
spelling doaj-art-597f2deacb6a4c9f98e43932e0e03b4e2025-08-20T03:34:39ZengWileyJournal of Skin Cancer2090-29052090-29132011-01-01201110.1155/2011/180980180980Grey-Blue Regression in Melanoma In Situ—Evaluation on 111 CasesS. Bassoli0S. Borsari1C. Ferrari2F. Giusti3G. Pellacani4G. Ponti5S. Seidenari6Department of Dermatology, University of Modena and Reggio Emilia, Modena, ItalyDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, ItalyDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, ItalyDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, ItalyDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, ItalyDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, ItalyDepartment of Dermatology, University of Modena and Reggio Emilia, Modena, ItalyAs fibrosis and melanosis are often seen in malignant melanoma, the presence of dermoscopic signs of regression may represent a clue for the diagnosis of malignancy. Our aim was to assess the frequency and extent of 11 dermoscopic features of regression evaluating dermoscopic images of 111 melanomas in situ (MIS). Regression structures (grey-blue areas, white areas, peppering, and/or blue-whitish veil) were present in 80.1% of the lesions. Approximately 80% of the lesions showed regression of dermoscopic structures and light brown areas. Most lesions showed the presence of grey-blue areas (74.7%), whereas peppering was observable in 30.6% of MIS. Areas of fibrosis were mainly observable as structureless areas with a pinkish hue (50.4%). Based on our data, the reticular pattern of blue regression and light brown areas can be considered a significant discriminator and a reliable predictor of MIS.http://dx.doi.org/10.1155/2011/180980
spellingShingle S. Bassoli
S. Borsari
C. Ferrari
F. Giusti
G. Pellacani
G. Ponti
S. Seidenari
Grey-Blue Regression in Melanoma In Situ—Evaluation on 111 Cases
Journal of Skin Cancer
title Grey-Blue Regression in Melanoma In Situ—Evaluation on 111 Cases
title_full Grey-Blue Regression in Melanoma In Situ—Evaluation on 111 Cases
title_fullStr Grey-Blue Regression in Melanoma In Situ—Evaluation on 111 Cases
title_full_unstemmed Grey-Blue Regression in Melanoma In Situ—Evaluation on 111 Cases
title_short Grey-Blue Regression in Melanoma In Situ—Evaluation on 111 Cases
title_sort grey blue regression in melanoma in situ evaluation on 111 cases
url http://dx.doi.org/10.1155/2011/180980
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