Platelet miRNAs as early biomarkers for progression of idiopathic REM sleep behavior disorder to a synucleinopathy

Platelet miRNAs as early biomarkers for progression of idiopathic REM sleep behavior disorder to a synucleinopathy

Abstract Individuals diagnosed with isolated REM sleep behavior disorder (IRBD) have a high risk of developing Lewy body disorders (LBD), mainly Parkinson’s disease (PD) or dementia with Lewy bodies (DLB). As we have previously identified seven platelet-derived miRNAs as potential biomarkers for DLB...

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Main Authors: Laura Arnaldo, Jorge Mena, Mònica Serradell, Carles Gaig, David Adamuz, Dolores Vilas, Daniela Samaniego, Lourdes Ispierto, Angelica Montini, Gerard Mayà, Ramiro Álvarez, Pau Pastor, Alex Iranzo, Katrin Beyer
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Isolated REM sleep behavior disorder
Lewy body disorders
Biomarkers
Platelets
MiRNA expression
Online Access:https://doi.org/10.1038/s41598-025-96926-3
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