Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia

Managing the blast phase in chronic myeloid leukemia (CML) is challenging because limited data are available for elderly patients. The involvement of the central nervous system (CNS) increases the risk of a poor prognosis. Here, we present an elderly blast phase CML patient with suspected CNS involv...

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Main Authors: Erden Atilla, Pinar Ataca, Elif Ozyurek, Ilhan Erden, Gunhan Gurman
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2015/689423
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author Erden Atilla
Pinar Ataca
Elif Ozyurek
Ilhan Erden
Gunhan Gurman
author_facet Erden Atilla
Pinar Ataca
Elif Ozyurek
Ilhan Erden
Gunhan Gurman
author_sort Erden Atilla
collection DOAJ
description Managing the blast phase in chronic myeloid leukemia (CML) is challenging because limited data are available for elderly patients. The involvement of the central nervous system (CNS) increases the risk of a poor prognosis. Here, we present an elderly blast phase CML patient with suspected CNS involvement who was successfully treated with bosutinib.
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institution DOAJ
issn 2090-6560
2090-6579
language English
publishDate 2015-01-01
publisher Wiley
record_format Article
series Case Reports in Hematology
spelling doaj-art-597c1113b7a148fea7ea70cbec2c4bce2025-08-20T03:19:25ZengWileyCase Reports in Hematology2090-65602090-65792015-01-01201510.1155/2015/689423689423Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid LeukemiaErden Atilla0Pinar Ataca1Elif Ozyurek2Ilhan Erden3Gunhan Gurman4Department of Hematology, Ankara University School of Medicine, 06590 Ankara, TurkeyDepartment of Hematology, Ankara University School of Medicine, 06590 Ankara, TurkeyDepartment of Radiology, Ankara University School of Medicine, 06590 Ankara, TurkeyDepartment of Radiology, Ankara University School of Medicine, 06590 Ankara, TurkeyDepartment of Hematology, Ankara University School of Medicine, 06590 Ankara, TurkeyManaging the blast phase in chronic myeloid leukemia (CML) is challenging because limited data are available for elderly patients. The involvement of the central nervous system (CNS) increases the risk of a poor prognosis. Here, we present an elderly blast phase CML patient with suspected CNS involvement who was successfully treated with bosutinib.http://dx.doi.org/10.1155/2015/689423
spellingShingle Erden Atilla
Pinar Ataca
Elif Ozyurek
Ilhan Erden
Gunhan Gurman
Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia
Case Reports in Hematology
title Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia
title_full Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia
title_fullStr Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia
title_full_unstemmed Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia
title_short Successful Bosutinib Experience in an Elderly Acute Lymphoblastic Leukemia Patient with Suspected Central Nervous System Involvement Transformed from Chronic Myeloid Leukemia
title_sort successful bosutinib experience in an elderly acute lymphoblastic leukemia patient with suspected central nervous system involvement transformed from chronic myeloid leukemia
url http://dx.doi.org/10.1155/2015/689423
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AT pinarataca successfulbosutinibexperienceinanelderlyacutelymphoblasticleukemiapatientwithsuspectedcentralnervoussysteminvolvementtransformedfromchronicmyeloidleukemia
AT elifozyurek successfulbosutinibexperienceinanelderlyacutelymphoblasticleukemiapatientwithsuspectedcentralnervoussysteminvolvementtransformedfromchronicmyeloidleukemia
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