Sputum Microbiota Compositions Correlate With Metabolome and Clinical Outcomes of COPD‐Bronchiectasis Association: A Prospective Cohort Study

Sputum Microbiota Compositions Correlate With Metabolome and Clinical Outcomes of COPD‐Bronchiectasis Association: A Prospective Cohort Study

ABSTRACT Bronchiectasis frequently co‐exists with chronic obstructive pulmonary disease (COPD‐bronchiectasis association [CBA]). We compared the microbiota and metabolome of bronchiectasis with (BO) and without airflow obstruction (BNO), COPD, and CBA. We determined how microbiota compositions corre...

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Main Authors: Zhen‐feng He, Xiao‐xian Zhang, Cui‐xia Pan, Xin‐zhu Yi, Yan Huang, Chun‐lan Chen, Shan‐shan Zha, Lai‐jian Cen, Han‐qin Cai, Lei Yang, Jia‐qi Gao, Hui‐min Li, Zhen‐hong Lin, Sheng‐zhu Lin, Zhang Wang, Nan‐shan Zhong, Wei‐jie Guan
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Exploration
Subjects:
Bronchiectasis
COPD
COPD‐Bronchiectasis association
exacerbation
metabolome
microbiota
Online Access:https://doi.org/10.1002/EXP.20240149
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