Serum immune indicators including IgM, IgA, and IgG levels and quality of life of patients with gastrointestinal tumours during chemotherapy
Background: Patients with gastrointestinal tumours often experience malnutrition and compromised immune function during chemotherapy, leading to a significant decline in quality of life. This study aimed to evaluate the effects of dietary nursing interventions on the nutritional status, immune funct...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Society of Medical Biochemists of Serbia, Belgrade
2025-01-01
|
| Series: | Journal of Medical Biochemistry |
| Subjects: | |
| Online Access: | https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2025/1452-82582504814W.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849427970766143488 |
|---|---|
| author | Wan Mengchao Wang Yunlong Zeng Lin Zhou Zhiyong Yao Weirong |
| author_facet | Wan Mengchao Wang Yunlong Zeng Lin Zhou Zhiyong Yao Weirong |
| author_sort | Wan Mengchao |
| collection | DOAJ |
| description | Background: Patients with gastrointestinal tumours often experience malnutrition and compromised immune function during chemotherapy, leading to a significant decline in quality of life. This study aimed to evaluate the effects of dietary nursing interventions on the nutritional status, immune function, and quality of life in patients undergoing chemotherapy. Methods: A total of 100 patients with gastrointestinal tumours receiving chemotherapy from January 2023 to June 2024 were randomly divided into two groups: a control group (CG) and a study group (SG). Both groups received conventional nursing interventions, but the SG also received dietary nursing interventions focused on personalized nutrition, dietary habits, and gastrointestinal health. Nutritional status was assessed using body mass index (BMI), haemoglobin (HGB), serum albumin (ALB), and oral mucosal cell apoptosis rate. Immune function was evaluated by measuring immunoglobulin M (IgM), immunoglobulin A (IgA), and immunoglobulin G (IgG) levels. Quality of life was measured using the GQOL-74 scale. Results: After the nursing interventions, the SG showed significant improvements in BMI, HGB, ALB, and oral mucosal cell apoptosis rate compared to the CG (P<0.05). Additionally, IgM, IgA, and IgG levels were significantly higher in the SG (P<0.05). Quality of life scores, including physical, social, psychological, and material life, also improved significantly in the SG compared to the CG (P<0.05). Conclusions: Dietary nursing interventions significantly improved the nutritional status, immune function, and quality of life of patients with gastrointestinal tumours undergoing chemotherapy. These findings underscore the importance of incorporating dietary care into nursing practices for cancer patients to support their overall well-being and treatment outcomes. |
| format | Article |
| id | doaj-art-59771c90cb9e46778322bf5e9f0e4eb9 |
| institution | Kabale University |
| issn | 1452-8258 1452-8266 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Society of Medical Biochemists of Serbia, Belgrade |
| record_format | Article |
| series | Journal of Medical Biochemistry |
| spelling | doaj-art-59771c90cb9e46778322bf5e9f0e4eb92025-08-20T03:28:51ZengSociety of Medical Biochemists of Serbia, BelgradeJournal of Medical Biochemistry1452-82581452-82662025-01-0144481482110.5937/jomb0-561371452-82582504814WSerum immune indicators including IgM, IgA, and IgG levels and quality of life of patients with gastrointestinal tumours during chemotherapyWan Mengchao0Wang Yunlong1Zeng Lin2Zhou Zhiyong3Yao Weirong4Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College Nanchang, Department of Clinic, Jiangxi, ChinaJiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Department of Oncology, Nanchang, Jiangxi, ChinaJiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Department of Oncology, Nanchang, Jiangxi, ChinaJiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Department of Oncology, Nanchang, Jiangxi, ChinaJiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Department of Oncology, Nanchang, Jiangxi, ChinaBackground: Patients with gastrointestinal tumours often experience malnutrition and compromised immune function during chemotherapy, leading to a significant decline in quality of life. This study aimed to evaluate the effects of dietary nursing interventions on the nutritional status, immune function, and quality of life in patients undergoing chemotherapy. Methods: A total of 100 patients with gastrointestinal tumours receiving chemotherapy from January 2023 to June 2024 were randomly divided into two groups: a control group (CG) and a study group (SG). Both groups received conventional nursing interventions, but the SG also received dietary nursing interventions focused on personalized nutrition, dietary habits, and gastrointestinal health. Nutritional status was assessed using body mass index (BMI), haemoglobin (HGB), serum albumin (ALB), and oral mucosal cell apoptosis rate. Immune function was evaluated by measuring immunoglobulin M (IgM), immunoglobulin A (IgA), and immunoglobulin G (IgG) levels. Quality of life was measured using the GQOL-74 scale. Results: After the nursing interventions, the SG showed significant improvements in BMI, HGB, ALB, and oral mucosal cell apoptosis rate compared to the CG (P<0.05). Additionally, IgM, IgA, and IgG levels were significantly higher in the SG (P<0.05). Quality of life scores, including physical, social, psychological, and material life, also improved significantly in the SG compared to the CG (P<0.05). Conclusions: Dietary nursing interventions significantly improved the nutritional status, immune function, and quality of life of patients with gastrointestinal tumours undergoing chemotherapy. These findings underscore the importance of incorporating dietary care into nursing practices for cancer patients to support their overall well-being and treatment outcomes.https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2025/1452-82582504814W.pdfgastrointestinal tumourschemotherapydietetics nursing interventionimmune functionnutritional statusquality of lifeigmigaigg |
| spellingShingle | Wan Mengchao Wang Yunlong Zeng Lin Zhou Zhiyong Yao Weirong Serum immune indicators including IgM, IgA, and IgG levels and quality of life of patients with gastrointestinal tumours during chemotherapy Journal of Medical Biochemistry gastrointestinal tumours chemotherapy dietetics nursing intervention immune function nutritional status quality of life igm iga igg |
| title | Serum immune indicators including IgM, IgA, and IgG levels and quality of life of patients with gastrointestinal tumours during chemotherapy |
| title_full | Serum immune indicators including IgM, IgA, and IgG levels and quality of life of patients with gastrointestinal tumours during chemotherapy |
| title_fullStr | Serum immune indicators including IgM, IgA, and IgG levels and quality of life of patients with gastrointestinal tumours during chemotherapy |
| title_full_unstemmed | Serum immune indicators including IgM, IgA, and IgG levels and quality of life of patients with gastrointestinal tumours during chemotherapy |
| title_short | Serum immune indicators including IgM, IgA, and IgG levels and quality of life of patients with gastrointestinal tumours during chemotherapy |
| title_sort | serum immune indicators including igm iga and igg levels and quality of life of patients with gastrointestinal tumours during chemotherapy |
| topic | gastrointestinal tumours chemotherapy dietetics nursing intervention immune function nutritional status quality of life igm iga igg |
| url | https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2025/1452-82582504814W.pdf |
| work_keys_str_mv | AT wanmengchao serumimmuneindicatorsincludingigmigaandigglevelsandqualityoflifeofpatientswithgastrointestinaltumoursduringchemotherapy AT wangyunlong serumimmuneindicatorsincludingigmigaandigglevelsandqualityoflifeofpatientswithgastrointestinaltumoursduringchemotherapy AT zenglin serumimmuneindicatorsincludingigmigaandigglevelsandqualityoflifeofpatientswithgastrointestinaltumoursduringchemotherapy AT zhouzhiyong serumimmuneindicatorsincludingigmigaandigglevelsandqualityoflifeofpatientswithgastrointestinaltumoursduringchemotherapy AT yaoweirong serumimmuneindicatorsincludingigmigaandigglevelsandqualityoflifeofpatientswithgastrointestinaltumoursduringchemotherapy |